Chemical synapses are heterogeneous junctions formed between neurons that are
specialized for the conversion of electrical impulses into the exocytotic release of …

Epidemiological estimates indicate that individuals with epilepsy are more likely to
experience headaches, including migraine, than individuals without epilepsy. Headaches …

Migraine is a common disabling brain disorder. A subtype of migraine with aura (familial
hemiplegic migraine type 2: FHM 2) is caused by loss‐of‐function mutations in α2 Na+, K+ …

Objective To review and discuss the literature on the role of cortical structure and function in
migraine. Discussion Structural and functional findings suggest that changes in cortical …

Migraine and epilepsy are episodic disorders with distinct features, but they have some
clinical and pathophysiological overlaps. We review here clinical overlaps between seizures …

Migraine is a common brain disorder with a large genetic component. Of the two main
migraine types, migraine with aura and migraine without aura, the genetic underpinning in …

Migraine and major depression are debilitating disorders with high lifetime prevalence rates.
Interestingly these disorders are highly comorbid and show significant heritability …

Migraine is a common multifactorial episodic brain disorder with strong genetic basis.
Monogenic subtypes include rare familial hemiplegic migraine, cerebral autosomal …

Mouse models of rare monogenic forms of migraine provide a unique experimental system
to study the cellular and circuit mechanisms of the primary brain dysfunctions causing a …

Generalized spike-wave seizures involving abnormal synchronization of cortical and
underlying thalamic circuitry represent a major category of childhood epilepsy. Inborn errors …