Lipid‐based nanoparticles for contrast‐enhanced MRI and molecular imaging

WJM Mulder, GJ Strijkers… - NMR in Biomedicine …, 2006 - Wiley Online Library
In the field of MR imaging and especially in the emerging field of cellular and molecular MR
imaging, flexible strategies to synthesize contrast agents that can be manipulated in terms of …

Molecular, cellular and functional imaging of atherothrombosis

RP Choudhury, V Fuster, ZA Fayad - Nature reviews Drug discovery, 2004 - nature.com
Recent years have seen a dramatic expansion in our knowledge of the events of
atherogenesis and in the availability of drugs that can retard the progression—and even …

Gadolinium nanoparticles as diagnostic and therapeutic agents: Their delivery systems in magnetic resonance imaging and neutron capture therapy

A Narmani, B Farhood, H Haghi-Aminjan… - Journal of Drug Delivery …, 2018 - Elsevier
Gadolinium (Gd) chelates have been widely used as contrast agent in magnetic resonance
imaging (MRI). In addition to using MRI, they are interesting, as a radiosensitizer, in neutron …

Molecular magnetic resonance imaging in cardiovascular medicine

DE Sosnovik, M Nahrendorf, R Weissleder - Circulation, 2007 - Am Heart Assoc
magnetofluorescent nanoparticle. 19, 20 In addition, many copies of the targeting ligand can
subsequently be attached to the CLIO-fluorochrome conjugate to form a multivalent (1 …

Lipid-rich atherosclerotic plaques detected by gadofluorine-enhanced in vivo magnetic resonance imaging

M Sirol, VV Itskovich, V Mani, JGS Aguinaldo… - Circulation, 2004 - Am Heart Assoc
Background—MRI of specific components in atherosclerotic plaque may provide information
on plaque stability and its potential to rupture. We evaluated gadofluorine in atherosclerotic …

Magnetic resonance imaging of vulnerable atherosclerotic plaques: current imaging strategies and molecular imaging probes

KC Briley‐Saebo, WJM Mulder, V Mani… - Journal of Magnetic …, 2007 - Wiley Online Library
The vulnerability or destabilization of atherosclerotic plaques has been directly linked to
plaque composition. Imaging modalities, such as magnetic resonance (MR) imaging, that …

Molecular imaging of macrophages in atherosclerotic plaques using bimodal PEG‐micelles

WJM Mulder, GJ Strijkers… - … in Medicine: An …, 2007 - Wiley Online Library
Pegylated, fluorescent, and paramagnetic micelles were developed. The micelles were
conjugated with macrophage scavenger receptor (MSR)‐specific antibodies. The abdominal …

Selective coronary artery plaque visualization and differentiation by contrast-enhanced inversion prepared MRI

D Maintz, M Ozgun, A Hoffmeier… - European heart …, 2006 - academic.oup.com
Aims We sought to evaluate the utility of contrast-enhanced coronary magnetic resonance
imaging (CE-MRI) for selective visualization and non-invasive differentiation of …

MRI of atherosclerosis in clinical trials

C Yuan, WS Kerwin, VL Yarnykh, J Cai… - NMR in Biomedicine …, 2006 - Wiley Online Library
Magnetic resonance imaging (MRI) of the arterial wall has emerged as a viable technology
for characterizing atherosclerotic lesions in vivo, especially within carotid arteries and other …

Metal containing nanosized systems for MR-molecular imaging applications

DD Castelli, E Gianolio, SG Crich, E Terreno… - Coordination Chemistry …, 2008 - Elsevier
This review aims at assessing the role of nanosized systems as MR-imaging reporters in
Molecular Imaging applications. The possibility of delivering a high number of imaging …