[HTML][HTML] Step by step: towards a better understanding of the genetic architecture of Alzheimer's disease
JC Lambert, A Ramirez, B Grenier-Boley… - Molecular …, 2023 - nature.com
Alzheimer's disease (AD) is considered to have a large genetic component. Our knowledge
of this component has progressed over the last 10 years, thanks notably to the advent of …
of this component has progressed over the last 10 years, thanks notably to the advent of …
[HTML][HTML] Short chain fatty acid metabolism in relation to gut microbiota and genetic variability
It is widely accepted that the gut microbiota plays a significant role in modulating
inflammatory and immune responses of their host. In recent years, the host-microbiota …
inflammatory and immune responses of their host. In recent years, the host-microbiota …
[HTML][HTML] SARS-CoV-2 is associated with changes in brain structure in UK Biobank
There is strong evidence of brain-related abnormalities in COVID-19,,,,,,,,,,,–. However, it
remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder …
remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder …
Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images
Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …
Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders
Observational studies have reported the correlations between brain imaging-derived
phenotypes (IDPs) and psychiatric disorders; however, whether the relationships are causal …
phenotypes (IDPs) and psychiatric disorders; however, whether the relationships are causal …
Replicable brain–phenotype associations require large-scale neuroimaging data
Numerous neuroimaging studies have investigated the neural basis of interindividual
differences but the replicability of brain–phenotype associations remains largely unknown …
differences but the replicability of brain–phenotype associations remains largely unknown …
[HTML][HTML] Discovery of 42 genome-wide significant loci associated with dyslexia
Reading and writing are crucial life skills but roughly one in ten children are affected by
dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up …
dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up …
Genome-wide analyses of individual differences in quantitatively assessed reading-and language-related skills in up to 34,000 people
E Eising, N Mirza-Schreiber… - Proceedings of the …, 2022 - National Acad Sciences
The use of spoken and written language is a fundamental human capacity. Individual
differences in reading-and language-related skills are influenced by genetic variation, with …
differences in reading-and language-related skills are influenced by genetic variation, with …
Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes
Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …
Brain imaging before and after COVID-19 in UK Biobank
There is strong evidence for brain-related pathologies in COVID-19, some of which could be
a consequence of viral neurotropism, or of neuroinflammation following viral infection. Most …
a consequence of viral neurotropism, or of neuroinflammation following viral infection. Most …