Shear-dependent platelet aggregation: mechanisms and therapeutic opportunities
A Rana, E Westein, B Niego… - Frontiers in cardiovascular …, 2019 - frontiersin.org
Cardiovascular diseases (CVD) are the number one cause of morbidity and death
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …
Enzymes inside lipid vesicles: preparation, reactivity and applications
P Walde, S Ichikawa - Biomolecular engineering, 2001 - Elsevier
There are a number of methods that can be used for the preparation of enzyme-containing
lipid vesicles (liposomes) which are lipid dispersions that contain water-soluble enzymes in …
lipid vesicles (liposomes) which are lipid dispersions that contain water-soluble enzymes in …
Understanding the immunogenicity and antigenicity of nanomaterials: Past, present and future
AN Ilinskaya, MA Dobrovolskaia - Toxicology and applied pharmacology, 2016 - Elsevier
Nanoparticle immunogenicity and antigenicity have been under investigation for many
years. During the past decade, significant progress has been made in understanding what …
years. During the past decade, significant progress has been made in understanding what …
Platelet microparticle-inspired clot-responsive nanomedicine for targeted fibrinolysis
CL Pawlowski, W Li, M Sun, K Ravichandran… - Biomaterials, 2017 - Elsevier
Intravascular administration of plasminogen activators is a clinically important thrombolytic
strategy to treat occlusive vascular conditions. A major issue with this strategy is the systemic …
strategy to treat occlusive vascular conditions. A major issue with this strategy is the systemic …
Application of nanotechnology in thrombus therapy
S Zhou, W Zhao, J Hu, C Mao… - Advanced Healthcare …, 2023 - Wiley Online Library
A thrombus is a blood clot that forms in the lumen of an artery or vein, restricting blood flow
and causing clinical symptoms. Thrombosis is associated with many life‐threatening …
and causing clinical symptoms. Thrombosis is associated with many life‐threatening …
Nanoparticles and the blood coagulation system. Part I: benefits of nanotechnology
AN Ilinskaya, MA Dobrovolskaia - Nanomedicine, 2013 - Taylor & Francis
Nanotechnology is proven to provide certain benefits in drug delivery by improving solubility,
increasing uptake to target sites and changing pharmacokinetics profiles of traditional drugs …
increasing uptake to target sites and changing pharmacokinetics profiles of traditional drugs …
Immunosuppressive and anti‐inflammatory properties of engineered nanomaterials
AN Ilinskaya, MA Dobrovolskaia - British journal of …, 2014 - Wiley Online Library
Nanoparticle interactions with various components of the immune system are determined by
their physicochemical properties such as size, charge, hydrophobicity and shape …
their physicochemical properties such as size, charge, hydrophobicity and shape …
The evolution of recombinant thrombolytics: Current status and future directions
Adivitiya, YP Khasa - Bioengineered, 2017 - Taylor & Francis
Cardiovascular disorders are on the rise worldwide due to alcohol abuse, obesity,
hypertension, raised blood lipids, diabetes and age-related risks. The use of classical …
hypertension, raised blood lipids, diabetes and age-related risks. The use of classical …
Therapeutic enzymes: discoveries, production and applications
Enzymes today play a predominant role in the pharmaceutical industries due to their ability
to efficiently and selectively catalyze biochemical reactions in living systems. Since the …
to efficiently and selectively catalyze biochemical reactions in living systems. Since the …
Advanced drug delivery systems for antithrombotic agents
CF Greineder, MD Howard… - Blood, The Journal …, 2013 - ashpublications.org
Despite continued achievements in antithrombotic pharmacotherapy, difficulties remain in
managing patients at high risk for both thrombosis and hemorrhage. Utility of antithrombotic …
managing patients at high risk for both thrombosis and hemorrhage. Utility of antithrombotic …