A guide to miRNAs in inflammation and innate immune responses
C Nejad, HJ Stunden, MP Gantier - The FEBS journal, 2018 - Wiley Online Library
The discovery of micro RNA s (miRNAs) in the early 1990's has revolutionized our thinking
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …
Why remission is not enough: underlying disease mechanisms in RA that prevent cure
Cure is the aspirational aim for the treatment of all diseases, including chronic inflammatory
conditions such as rheumatoid arthritis (RA); however, it has only been during the twenty …
conditions such as rheumatoid arthritis (RA); however, it has only been during the twenty …
[HTML][HTML] miRNAs as biomarkers and possible therapeutic strategies in rheumatoid arthritis
T Kmiołek, A Paradowska-Gorycka - Cells, 2022 - mdpi.com
Within the past years, more and more attention has been devoted to the epigenetic
dysregulation that provides an additional window for understanding the possible …
dysregulation that provides an additional window for understanding the possible …
[HTML][HTML] Comprehensive overview of microRNA function in rheumatoid arthritis
X Peng, Q Wang, W Li, G Ge, J Peng, Y Xu, H Yang… - Bone Research, 2023 - nature.com
MicroRNAs (miRNAs), a class of endogenous single-stranded short noncoding RNAs, have
emerged as vital epigenetic regulators of both pathological and physiological processes in …
emerged as vital epigenetic regulators of both pathological and physiological processes in …
[HTML][HTML] Circulating miRNAs as potential biomarkers of therapy effectiveness in rheumatoid arthritis patients treated with anti-TNFα
C Castro-Villegas, C Pérez-Sánchez… - Arthritis research & …, 2015 - Springer
Introduction The advent of anti-tumor necrosis factor alpha (anti-TNFα) drugs has
considerably improved medical management in rheumatoid arthritis (RA) patients, although …
considerably improved medical management in rheumatoid arthritis (RA) patients, although …
[HTML][HTML] microRNA diagnostic panel for Alzheimer's disease and epigenetic trade-off between neurodegeneration and cancer
S Nagaraj, KM Zoltowska, K Laskowska-Kaszub… - Ageing research …, 2019 - Elsevier
Abstract microRNAs (miRNAs) have been extensively studied as potential biomarkers for
Alzheimer's disease (AD). Their profiles have been analyzed in blood, cerebrospinal fluid …
Alzheimer's disease (AD). Their profiles have been analyzed in blood, cerebrospinal fluid …
[HTML][HTML] miR-221-3p drives the shift of M2-macrophages to a pro-inflammatory function by suppressing JAK3/STAT3 activation
L Quero, AN Tiaden, E Hanser, J Roux, A Laski… - Frontiers in …, 2020 - frontiersin.org
Objectives: Macrophages are conventionally classified as pro-inflammatory (M1) and anti-
inflammatory (M2) functional types. There is evidence for a predominance of macrophages …
inflammatory (M2) functional types. There is evidence for a predominance of macrophages …
[HTML][HTML] The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis
J Yang, Z Li, L Wang, X Yun, Y Zeng, JPL Ng… - Pharmacological …, 2022 - Elsevier
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disorder which is associated
with the dysregulation of autoimmune response. In recent years, early diagnosis, aggressive …
with the dysregulation of autoimmune response. In recent years, early diagnosis, aggressive …
[HTML][HTML] Serum miRNA signature in rheumatoid arthritis and “at-risk individuals”
CC Cunningham, S Wade, A Floudas, C Orr… - Frontiers in …, 2021 - frontiersin.org
Background MicroRNAs (miRNAs) are small non-coding RNAs which have been implicated
as potential biomarkers or therapeutic targets in autoimmune diseases. This study examines …
as potential biomarkers or therapeutic targets in autoimmune diseases. This study examines …
[HTML][HTML] Circulating microRNA biomarkers as liquid biopsy for cancer patients: pros and cons of current assays
S Ono, S Lam, M Nagahara, DSB Hoon - Journal of clinical medicine, 2015 - mdpi.com
An increasing number of studies have focused on circulating microRNAs (cmiRNA) in
cancer patients' blood for their potential as minimally-invasive biomarkers. Studies have …
cancer patients' blood for their potential as minimally-invasive biomarkers. Studies have …