Functional interactions between lncRNAs/circRNAs and miRNAs: insights into rheumatoid arthritis

JJ Han, XQ Wang, XA Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases that affect
synovitis, bone, cartilage, and joint. RA leads to bone and cartilage damage and extra …

Implications the Role of miR-155 in the Pathogenesis of Autoimmune Diseases

S Pashangzadeh, M Motallebnezhad… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are small noncoding conserved RNAs containing 19 to 24 nucleotides
that are regulators of post-translational modifications and are involved in the majority of …

Rheumatoid arthritis and miRNAs: a critical review through a functional view

MC Moran-Moguel, S Petarra-del Rio… - Journal of …, 2018 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic autoimmune disease with severe joint inflammation
and destruction associated with an inflammatory environment. The etiology behind RA …

Epigenetics in the pathogenesis of RA

C Ospelt, S Gay, K Klein - Seminars in immunopathology, 2017 - Springer
Epigenetic modifications can stably alter gene expression and have been shown to be
important in the maintenance of cell type-specific functions as well as in cell differentiation …

Circulating miRNAs in cancer: from detection to therapy

WT Wang, YQ Chen - Journal of hematology & oncology, 2014 - Springer
Since the discovery of circulating microRNAs (miRNAs) in body fluids, an increasing number
of studies have focused on their potential as non-invasive biomarkers and as therapeutic …

Circulating miRNAs in bone health and disease

J Grillari, RE Mäkitie, R Kocijan, J Haschka… - Bone, 2021 - Elsevier
Abstract microRNAs have evolved as important regulators of multiple biological pathways
essential for bone homeostasis, and microRNA research has furthered our understanding of …

Epigenetics in autoimmune diseases: pathogenesis and prospects for therapy

Z Zhang, R Zhang - Autoimmunity reviews, 2015 - Elsevier
Epigenetics is the study of heritable changes in genome function without underlying
modifications in their nucleotide sequence. Disorders of epigenetic processes, which involve …

Deregulation of microRNA expression in purified T and B lymphocytes from patients with primary Sjögren's syndrome

SF Wang-Renault, S Boudaoud, G Nocturne… - Annals of the …, 2018 - ard.bmj.com
Objective MicroRNAs (miRNAs) play an important role in the pathogenesis of autoimmune
diseases such as primary Sjögren's syndrome (pSS). This study is the first to investigate …

[PDF][PDF] RETRACTED: Dysregulation of Survivin-Targeting microRNAs in Autoimmune Diseases: New Perspectives for Novel Therapies

N Shomali, M Suliman Maashi, B Baradaran… - Frontiers in …, 2022 - frontiersin.org
It has been well established that the etiopathogenesis of diverse autoimmune diseases is
rooted in the autoreactive immune cells' excessively proliferative state and impaired …

Epigenetic control of autoimmune diseases: from bench to bedside

A Picascia, V Grimaldi, O Pignalosa, MR De Pascale… - Clinical …, 2015 - Elsevier
Genome-wide association studies have revealed several genes predisposing to
autoimmunity, however, concordance rates in monozygotic twins are significantly below …