[HTML][HTML] Notch-regulated miR-223 targets the aryl hydrocarbon receptor pathway and increases cytokine production in macrophages from rheumatoid arthritis patients

J Ogando, M Tardáguila, A Díaz-Alderete, A Usategui… - Scientific reports, 2016 - nature.com
Evidence links aryl hydrocarbon receptor (AHR) activation to rheumatoid arthritis (RA)
pathogenesis, although results are inconsistent. AHR agonists inhibit pro-inflammatory …

Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression

C Angiolilli, AM Grabiec, BS Ferguson… - Annals of the …, 2016 - ard.bmj.com
Objectives Epigenetic modifications play an important role in the regulation of gene
transcription and cellular function. Here, we examined if pro-inflammatory factors present in …

Prediction of treatment response to adalimumab: a double-blind placebo-controlled study of circulating microRNA in patients with early rheumatoid arthritis

SB Krintel, C Dehlendorff, ML Hetland… - The …, 2016 - nature.com
At least 30% of patients with rheumatoid arthritis (RA) do not respond to biologic agents,
which emphasizes the need of predictive biomarkers. We aimed to identify microRNAs …

[HTML][HTML] Plasma expression of microRNA-425-5p and microRNA-451a as biomarkers of cardiovascular disease in rheumatoid arthritis patients

D Taverner, D Llop, R Rosales, R Ferré, L Masana… - Scientific Reports, 2021 - nature.com
To validate in a cohort of 214 rheumatoid arthritis patients a panel of 10 plasmatic
microRNAs, which we previously identified and that can facilitate earlier diagnosis of …

Novel anti-inflammatory target of geniposide: inhibiting Itgβ1/Ras-Erk1/2 signal pathway via the miRNA-124a in rheumatoid arthritis synovial fibroblasts

Y Wang, L Dai, H Wu, Z Zhang, W Wang, J Fu… - International …, 2018 - Elsevier
Geniposide (GE) is an active component isolated from the fruit of Gardenia jasminoides Ellis
that has anti-inflammatory and other pharmacological effects; however, the underlying …

[HTML][HTML] X-linked miRNAs associated with gender differences in rheumatoid arthritis

O Khalifa, YM Pers, R Ferreira, A Sénéchal… - International journal of …, 2016 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that predominantly affects women.
MicroRNAs have emerged as crucial regulators of the immune system, whose expression is …

[HTML][HTML] Epigenetic regulation (Including micro-rnas, dna methylation and histone modifications) of rheumatoid arthritis: a systematic review

M Payet, F Dargai, P Gasque, X Guillot - International Journal of …, 2021 - mdpi.com
The inflammatory reaction in rheumatoid arthritis (RA) is controlled by major epigenetic
modifications that modulate the phenotype of synovial and immune cells. The aim of this …

Upregulation of miR-221/222 expression in rheumatoid arthritis (RA) patients: correlation with disease activity

AS Abo ElAtta, YBM Ali, IH Bassyouni… - Clinical and experimental …, 2019 - Springer
Abstract miRNAs are noncoding RNA that play a critical role as fine regulators of gene
expression at the posttranscriptional level within cells in numerous autoimmune diseases …

[HTML][HTML] The role of microRNA-16 in the pathogenesis of autoimmune diseases: A comprehensive review

L Yan, M Liang, X Hou, Y Zhang, H Zhang… - Biomedicine & …, 2019 - Elsevier
MicroRNAs (miRNAs) are a class of small noncoding RNAs that are only 21–25 nt long.
Many studies have shown that miRNA dysfunction is closely related to the occurrence and …

[HTML][HTML] MicroRNA-125b: association with disease activity and the treatment response of patients with early rheumatoid arthritis

V Hruskova, R Jandova, L Vernerova, H Mann… - Arthritis research & …, 2016 - Springer
Background MicroRNAs (miRNAs) are small RNAs that regulate gene expression by
targeting mRNA. It was proved that some miRNAs are significantly deregulated in …