Insights of rheumatoid arthritis biomarkers

B Kolarz, D Podgorska, R Podgorski - Biomarkers, 2021 - Taylor & Francis
Rheumatoid arthritis is a chronic, autoimmune connective tissue disease. In addition to joint
involvement, extra-articular changes and organ complications also occur in the course of the …

Plasma miRNA-223 correlates with risk, inflammatory markers as well as prognosis in sepsis patients

X Wu, J Yang, L Yu, D Long - Medicine, 2018 - journals.lww.com
Plasma miRNA-223 correlates with risk, inflammatory markers... : Medicine Plasma miRNA-223
correlates with risk, inflammatory markers as well as prognosis in sepsis patients : Medicine Log …

Utility of select plasma microRNA for disease and cardiovascular risk assessment in patients with rheumatoid arthritis

MJ Ormseth, JF Solus, KC Vickers, AM Oeser… - The Journal of …, 2015 - jrheum.org
Objective. MicroRNA (miRNA) are small noncoding RNA that posttranscriptionally regulate
gene expression and serve as potential mediators and markers of disease. Recently …

MicroRNAs and bioactive compounds on TLR/MAPK signaling in rheumatoid arthritis

S Sujitha, M Rasool - Clinica Chimica Acta, 2017 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune mediated joint disease with severe
complications affecting 1% of the population worldwide. Although the exact mechanism …

A review of liquid biopsy as a tool to assess epigenetic, cfDNA and miRNA variability as methotrexate response predictors in patients with rheumatoid arthritis

DN Daraghmeh, C King, MD Wiese - Pharmacological Research, 2021 - Elsevier
Rheumatoid arthritis (RA) is a common autoimmune inflammatory disease affecting 0.5–1%
of adults worldwide. Achieving long term remission or low disease activity is possible …

Physical activity as a preventive lifestyle intervention acts through specific exosomal miRNA species—evidence from human short-and long-term pilot studies

K Garai, Z Adam, R Herczeg, K Banfai… - Frontiers in …, 2021 - frontiersin.org
Exercise initiates systemic adaptation to promote health and prevent various lifestyle-related
chronic diseases. Emerging evidence suggests that circulating exosomes mediate some of …

MicroRNAs in rheumatoid arthritis

E Salehi, R Eftekhari, M Oraei, A Gharib, K Bidad - Clinical rheumatology, 2015 - Springer
The role of genetic and epigenetic factors in the development of rheumatic diseases has
been an interesting field of research over the past decades all around the world. Research …

Association between circulating miRNAs and spinal involvement in patients with axial spondyloarthritis

K Prajzlerová, K Grobelná, M Hušáková, Š Forejtová… - PLoS …, 2017 - journals.plos.org
Objectives Dysregulation of miRNAs and their target genes contributes to the
pathophysiology of autoimmune diseases. Circulating miRNAs may serve as …

MicroRNA-146a governs fibroblast activation and joint pathology in arthritis

V Saferding, A Puchner, E Goncalves-Alves… - Journal of …, 2017 - Elsevier
Synovial fibroblasts are key cells orchestrating the inflammatory response in arthritis. Here
we demonstrate that loss of miR-146a, a key epigenetic regulator of the innate immune …

miR-410-3p suppresses cytokine release from fibroblast-like synoviocytes by regulating NF-κB signaling in rheumatoid arthritis

YJ Wang, NL Xu, S Zhao, T Jiao, WY Fu, LL Yang… - Inflammation, 2019 - Springer
Abstract miR-410-3p acts as an oncogene or a tumor suppressor in some malignancies.
However, its role in rheumatoid arthritis (RA) is unknown. The study was conducted to …