microRNA-130b downregulation potentiates chondrogenic differentiation of bone marrow mesenchymal stem cells by targeting SOX9

P Zhang, G Gao, Z Zhou, X He - Brazilian Journal of Medical and …, 2021 - SciELO Brasil
Osteoarthritis (OA) is a chronic health condition. MicroRNAs (miRs) are critical in
chondrocyte apoptosis in OA. We aimed to investigate the mechanism of miR-130b in OA …

Upregulated expression of microRNA-16 correlates with Th17/Treg cell imbalance in patients with rheumatoid arthritis

YH Wu, W Liu, B Xue, L Zhang, XY Liu, B Liu… - DNA and cell …, 2016 - liebertpub.com
To explore the correlation between miR-16 expression in T cells of peripheral blood
mononuclear cells (PBMCs) and Th17/Treg imbalance in rheumatoid arthritis (RA) patients …

[PDF][PDF] Plasma micro-RNA-22 is associated with disease activity in well-established rheumatoid arthritis

M Cieśla, B Kolarz, M Majdan… - Clin Exp …, 2022 - clinexprheumatol.org
Objective Micro-RNAs (miRNAs) are an endogenous small, single-stranded, non-coding
RNAs with a 18-25 nucleotide long and have been reported as potential extracellular …

[PDF][PDF] Identification of circulating miR-22-3p and let-7a-5p as novel diagnostic biomarkers for rheumatoid arthritis

J Tang, J Lin, Z Yu, R Jiang, J Xia, B Yang… - Clin Exp …, 2022 - clinexprheumatol.org
Identification of circulating miR-22-3p and let-7a-5p as novel diagnostic biomarkers for
rheumatoid arthritis Page 1 Clinical and Experimental Rheumatology 2022 Clinical and …

[PDF][PDF] miR-212-3p reduced proliferation, and promoted apoptosis of fibroblast-like synoviocytes via down-regulating SOX5 in rheumatoid arthritis.

Y Liu, XL Zhang, XF Li, YC Tang… - European Review for …, 2018 - europeanreview.org
OBJECTIVE: Several microRNAs have been reported to contribute the progression of
rheumatoid arthritis (RA) due to the ectopic expression of miRNAs in fibroblast-like …

[HTML][HTML] Functional polymorphisms in pre-miR146a and pre-miR499 are associated with systemic lupus erythematosus but not with rheumatoid arthritis or Graves' …

I Alemán-Ávila, M Jiménez-Morales… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Recently, different microRNA (miRNA) gene polymorphisms have been evaluated in
patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Graves' …

MicroRNAs in rheumatoid arthritis: what is the latest with regards to diagnostics?

RY Huang, JQ Wu, ZH Liu, SL Sun - Expert Review of Molecular …, 2019 - Taylor & Francis
Rheumatoid arthritis (RA) is a systemic, chronic and inflammatory disease with unknown
etiology [1]. Characteristic features of RA are chronic synovitis and a fluctuating clinical …

MicroRNA-mediated immune regulation in rheumatic diseases

IKY Lam, JX Chow, CS Lau, VSF Chan - Cancer Letters, 2018 - Elsevier
MicroRNAs (miRNAs) are endogenous small, non-coding RNAs that regulate genome
expression at the post-transcriptional level. They are involved in a wide range of …

[HTML][HTML] Utility of circulating serum miRNAs as biomarkers of early cartilage degeneration in animal models of post-traumatic osteoarthritis and inflammatory arthritis

LHW Kung, S Zaki, V Ravi, L Rowley, MM Smith… - Osteoarthritis and …, 2017 - Elsevier
Objective The purpose of this study was to determine if serum microRNA (miRNA)
signatures were biomarkers of early cartilage degeneration in preclinical mouse models of …

Serum a proliferation-inducing ligand and MicroRNA-223 are associated with rheumatoid arthritis: diagnostic and prognostic implications

M Taha, OG Shaker, E Abdelsalam, N Taha - Molecular medicine, 2020 - Springer
Background Current blood-based tests for rheumatoid arthritis (RA) have inherent
limitations, necessitating the need for additional new biomarkers for its diagnosis and …