miRNA-Mediated Epigenetic Regulation of Treatment Response in RA Patients—A Systematic Review

A Mucientes, JM Lisbona, N Mena-Vázquez… - International Journal of …, 2022 - mdpi.com
This study aimed to evaluate the role of microRNAs (miRNA) as biomarkers of treatment
response in rheumatoid arthritis (RA) patients through a systematic review of the literature …

Identification of putative miRNA biomarkers in early rheumatoid arthritis by genome-wide microarray profiling: a pilot study

MF Romo-García, Y Bastian, M Zapata-Zuñiga… - Gene, 2019 - Elsevier
Despite the existing research, the etiology of rheumatoid arthritis (RA), an autoimmune
disease remains poorly understood with early and accurate diagnosis difficult to achieve …

Micro-RNA content of circulating extracellular vesicles in early rheumatoid arthritis as biomarkers and mediators of methotrexate efficacy

D Maunder, PM Brown, B Barron-Millar… - …, 2023 - academic.oup.com
Abstract Objectives Extracellular vesicles (EVs) are abundant in body fluids, contributing to
intercellular signalling by transferring cargo that includes microRNAs (miRs)—themselves …

Serum microRNAs as potential biomarkers of juvenile idiopathic arthritis

Y Kamiya, J Kawada, Y Kawano, Y Torii, S Kawabe… - Clinical …, 2015 - Springer
MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression of targeted
mRNAs, which are important in the pathogenesis of autoimmune diseases. MiRNAs may …

Exploring the impact of miR-128 in inflammatory diseases: A comprehensive study on autoimmune diseases

R Margiana, HH Kzar, F Hussam, NM Hameed… - … -Research and Practice, 2023 - Elsevier
Abstract microRNAs (miRNAs) play a crucial role in various biological processes, including
immune system regulation, such as cell proliferation, tolerance (central and peripheral), and …

Functional regulation of macrophage phenotypes by microRNAs in inflammatory arthritis

X Niu, GS Schulert - Frontiers in Immunology, 2019 - frontiersin.org
Inflammatory arthritis including rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA)
exhibit the shared feature of changes in activation and polarization of circulating monocytes …

Circulating extracellular microRNA in systemic autoimmunity

NHH Heegaard, AL Carlsen, K Skovgaard… - … microRNAs in Disease …, 2015 - Springer
MicroRNAs (miRNAs) are differentially regulated in healthy, activated, inflamed, neoplastic,
or otherwise pathological cells and tissues. While their main functions are executed …

[HTML][HTML] Upregulation of CD4+ T-cell derived MiR-223 in the relapsing phase of multiple sclerosis patients

A Hosseini, K Ghaedi, S Tanhaei… - Cell Journal …, 2016 - ncbi.nlm.nih.gov
Objective MicroRNAs (miRNA) are a class of non-coding RNAs which play key roles in post-
transcriptional gene regulation. Previous studies indicate that miRNAs are dysregulated in …

Exploring the extracellular vesicle MicroRNA expression repertoire in patients with rheumatoid arthritis and ankylosing spondylitis treated with TNF inhibitors

J Wielińska, RE Crossland, P Łacina… - Disease …, 2021 - Wiley Online Library
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) belong to the most common
inflammatory rheumatic diseases. MicroRNAs (miRNAs) are small 18–22 RNA molecules …

High miR-451 expression in peripheral blood mononuclear cells from subjects at risk of developing rheumatoid arthritis

K Prajzlerová, O Kryštůfková, P Hánová… - Scientific reports, 2021 - nature.com
Individuals carrying anti-citrullinated protein antibodies (ACPA) are considered at high risk
of developing rheumatoid arthritis (RA). The altered expression of miRNAs contributes to the …