Chronic psychosocial stress is increasingly recognized as a risk factor for late-onset
Alzheimer's disease (LOAD) and associated cognitive deficits. Chronic stress also primes …

Over the past several decades a large amount of data have established that glial cells, the
main cell population in the brain, dynamically interact with neurons and thus impact their …

Astrocytes support the energy demands of synaptic transmission and plasticity. Enduring
changes in synaptic efficacy are highly sensitive to stress, yet whether changes to astrocyte …

The principle functions of neuroinflammation are to limit tissue damage and promote tissue
repair in response to pathogens or injury. While neuroinflammation has utility …

Now astrocytes appear to be the key contributors to the pathophysiology of major
depression. Evidence in rodents shows that chronic stress is associated with a decreased …

Ischemic stroke is a multi-factorial cerebrovascular disease with high worldwide morbidity
and mortality. In the past few years, multiple studies have revealed the underlying …

There is an increasing risk of mental disorders, such as acute stress disorder (ASD), post-
traumatic stress disorder (PTSD) and depression among survivors who were trapped in …

Psychiatric disorders describe different mental or behavioral patterns, causing suffering or
poor coping of ordinary life with manifold presentations. Multifactorial processes can …

Microglia represent the immune system of the brain. Their role is central in two phenomena,
neuroinflammation and oxidative stress, which are at the roots of different pathologies …

Astrocytes play a crucial role in the maintenance of the normal functions of the Central
Nervous System (CNS). During the pathogenesis of neurodegenerative diseases, astrocytes …