[HTML][HTML] Nutrition and metabolic adaptations in physiological and complicated pregnancy: focus on obesity and gestational diabetes

S Parrettini, A Caroli, E Torlone - Frontiers in endocrinology, 2020 - frontiersin.org
Pregnancy offers a window of opportunity to program the future health of both mothers and
offspring. During gestation, women experience a series of physical and metabolic …

[HTML][HTML] Prenatal psychological or metabolic stress increases the risk for psychiatric disorders: the “funnel effect” model

C Musillo, A Berry, F Cirulli - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Adverse stressful experiences in utero can redirect fetal brain development, ultimately
leading to increased risk for psychiatric disorders. Obesity during pregnancy can have …

[HTML][HTML] Immune-metabolic adaptations in pregnancy: A potential stepping-stone to sepsis

S Sharma, PRS Rodrigues, S Zaher, LC Davies… - …, 2022 - thelancet.com
Physiological shifts during pregnancy predispose women to a higher risk of developing
sepsis resulting from a maladapted host-response to infection. Insightful studies have …

[HTML][HTML] Exposure to endocrine disrupting chemicals impacts immunological and metabolic status of women during pregnancy

AK Merrill, M Sobolewski, M Susiarjo - Molecular and Cellular …, 2023 - Elsevier
Pregnancy is a unique physiological window for maternal and fetal health. Disorders that
arise during pregnancy influence the survival and health outcomes of mother and baby …

[HTML][HTML] Maternal microbiota and gestational diabetes: impact on infant health

P Singh, DAI Elhaj, I Ibrahim, H Abdullahi… - Journal of Translational …, 2023 - Springer
Gestational diabetes mellitus (GDM) is a common complication of pregnancy that has been
associated with an increased risk of obesity and diabetes in the offspring. Pregnancy is …

[HTML][HTML] Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity

AK Anam, KM Cooke, MB Dratver, JV O'Bryan… - Molecular …, 2022 - Elsevier
Objective Maternal obesity increases the incidence of excess adiposity in newborns,
resulting in lifelong diabetes risk. Elevated intrauterine fetal adiposity has been attributed to …

[HTML][HTML] The potential for placental activation of PPARγ to improve the angiogenic profile in preeclampsia

B Grimaldi, HR Kohan-Ghadr, S Drewlo - Cells, 2022 - mdpi.com
Preeclampsia (PE) is one of the most common causes of maternal-fetal morbidity and
mortality world-wide. While the underlying causes of PE remain elusive, aberrant trophoblast …

[HTML][HTML] Irisin and the fibronectin type III domain-containing family: structure, signaling and role in female reproduction

M Daudon, Y Bigot, J Dupont, CA Price - Reproduction, 2022 - rep.bioscientifica.com
In Brief Hormones secreted by muscle cells (myokines) are involved in the adaptive
response to nutritional and metabolic changes. In this review, we discuss how one family of …

Angiotensin-converting enzyme 2 (ACE2), angiotensin-(1-7) and Mas receptor in gonadal and reproductive functions

FM Reis, AM Reis - Clinical Science, 2020 - portlandpress.com
Abstract Angiotensin (Ang)-(1-7) is an active peptide formed from Ang I or Ang-(1-9) by
multiple proteolytic steps involving angiotensin-converting enzyme (ACE) 1 and other …

[HTML][HTML] The complete change in bile acids and steroids in systematic metabolomics applied to the intrahepatic cholestasis of pregnancy

H Xu, Y Xu, G Zhao, X Fu, J Zhao, H Wang, Y Cai… - Molecular …, 2023 - pubs.rsc.org
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific hepatobiliary disease,
leading to an abnormal increase in total bile acid in the blood of pregnant women. To …