Introduction: We investigated the possibilities and opportunities for using wearable devices
that measure physical activity and physiometric signals in conjunction with ecological …

For decades, basic research on the underlying mechanisms of nociception has held promise
to translate into efficacious treatments for patients with pain. Despite great improvement in …

Abstract The Helping to End Addiction Long-term SM Initiative (NIH HEAL Initiative SM) is an
aggressive trans-NIH effort to speed solutions to stem the national opioid public health crisis …

Purpose of Review A multimodal analgesic approach improves postoperative pain relief and
reduces opioid use; however, it is not universally implemented. This review presents the …

More than 300 million patients undergo surgery worldwide each year. Pain associated with
these procedures is associated with short-and long-term negative sequelae for patients …

Background Pain is the leading cause of disability worldwide among adults and effective
treatment options remain elusive. Data harmonization efforts, such as through core outcome …

Abstract Background and Objective Recently, a consensus process specified a core
outcome set (COS) of domains to be assessed in each comparative effectiveness research …

Chronic pain is a constantly recurring and persistent illness, presenting a formidable
healthcare challenge for patients and physicians alike. Current first‐line analgesics offer …

Background Chronic pain is the leading cause of disability. Improving our understanding of
pain occurrence and treatment effectiveness requires robust methods to measure pain at …

The management of acute postoperative pain remains suboptimal. Systematic reviews and
Cochrane analysis can assist with collating evidence about treatment efficacy, but the results …