[HTML][HTML] Endoplasmic reticulum stress: a novel targeted approach to repair bone defects by regulating osteogenesis and angiogenesis
T Wu, Y Jiang, W Shi, Y Wang, T Li - Journal of Translational Medicine, 2023 - Springer
Bone regeneration therapy is clinically important, and targeted regulation of endoplasmic
reticulum (ER) stress is important in regenerative medicine. The processing of proteins in the …
reticulum (ER) stress is important in regenerative medicine. The processing of proteins in the …
[HTML][HTML] Recent advances in mitochondrial fission/fusion-targeted therapy in doxorubicin-induced cardiotoxicity
Doxorubicin (DOX) has been recognized as one of the most effective chemotherapies and
extensively used in the clinical settings of human cancer. However, DOX-mediated …
extensively used in the clinical settings of human cancer. However, DOX-mediated …
[HTML][HTML] Role of mitochondria in doxorubicin-mediated cardiotoxicity: from molecular mechanisms to therapeutic strategies
T Wang, G Xing, T Fu, Y Ma, Q Wang, S Zhang… - Cell Stress and …, 2024 - Elsevier
This comprehensive review delves into the pivotal role of mitochondria in doxorubicin-
induced cardiotoxicity, a significant complication limiting the clinical use of this potent …
induced cardiotoxicity, a significant complication limiting the clinical use of this potent …
Doxorubicin-mediated cardiac dysfunction: Revisiting molecular interactions, pharmacological compounds and (nano) theranostic platforms
X Li - Environmental Research, 2023 - Elsevier
Although chemotherapy drugs are extensively utilized in cancer therapy, their administration
for treatment of patients has faced problems that regardless of chemoresistance, increasing …
for treatment of patients has faced problems that regardless of chemoresistance, increasing …
[HTML][HTML] Lady's Bedstraw as a powerful antioxidant for attenuation of doxorubicin-induced cardiotoxicity
J Bradic, M Andjic, J Novakovic, A Kocovic, M Tomovic… - Antioxidants, 2023 - mdpi.com
This study aimed to examine the effects of a 14-day treatment with lady's bedstraw methanol
extract on doxorubicin-induced cardiotoxicity through functional, biochemical and …
extract on doxorubicin-induced cardiotoxicity through functional, biochemical and …
[HTML][HTML] TGR5 supresses cGAS/STING pathway by inhibiting GRP75-mediated endoplasmic reticulum-mitochondrial coupling in diabetic retinopathy
Y Li, L Zhu, MX Cai, ZL Wang, M Zhuang, CY Tan… - Cell Death & …, 2023 - nature.com
Diabetic retinopathy (DR) is a serious and relatively under-recognized complication of
diabetes. Müller glial cells extend throughout the retina and play vital roles in maintaining …
diabetes. Müller glial cells extend throughout the retina and play vital roles in maintaining …
Two polyphenols isolated from Corallodiscus flabellata BL Burtt ameliorate amyloid β-protein induced Alzheimer's disease neuronal injury by improving mitochondrial …
B Cao, M Zeng, F Hao, C Zhao, B Zhang, Y Wu… - Behavioural Brain …, 2023 - Elsevier
Abstract Corallodiscus flabellata BL Burtt (CF) is a Chinese folk herb with reported potential
for the treatment of Alzheimer's disease (AD). 3, 4-Dihydroxyphenylethanol-8-O-[4-O-trans …
for the treatment of Alzheimer's disease (AD). 3, 4-Dihydroxyphenylethanol-8-O-[4-O-trans …
[HTML][HTML] Cardioprotective potentials of myricetin on doxorubicin-induced cardiotoxicity based on biochemical and transcriptomic analysis
J Li, T Luo, Y Zhao, D Wang, Y Jin, Z Wu… - Biomedicine & …, 2024 - Elsevier
Doxorubicin (DOX) is a commonly used anthracycline in cancer chemotherapy. The clinical
application of DOX is constrained by its cardiotoxicity. Myricetin (MYR) is a natural flavonoid …
application of DOX is constrained by its cardiotoxicity. Myricetin (MYR) is a natural flavonoid …
[HTML][HTML] Bioactive compounds and cardiac fibrosis: current insight and future prospect
Cardiac fibrosis is a pathological condition characterized by excessive deposition of
collagen and other extracellular matrix components in the heart. It is recognized as a major …
collagen and other extracellular matrix components in the heart. It is recognized as a major …
Integrated network analysis and experimental verification of the mechanisms employed by Compound Jixuecao Decoction to improve endoplasmic reticulum stress …
H Zheng, J Zeng, P Bi, W Xu, Y Yang, H Chen… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Compound Jixuecao Decoction (CJD) is a
traditional Chinese herbal medicine prescribed in China to treat chronic renal failure (CRF) …
traditional Chinese herbal medicine prescribed in China to treat chronic renal failure (CRF) …