Clinical pharmacokinetics and pharmacodynamics of ceftazidime–avibactam combination: a model-informed strategy for its clinical development

SKB Sy, L Zhuang, S Sy, H Derendorf - Clinical Pharmacokinetics, 2019 - Springer
Avibactam is a non-β-lactam, β-lactamase inhibitor of the diazabicyclooctane class that
covalently acylates its β-lactamase targets, encompassing extended spectrum of activities …

Isolation and Identification of Multidrug-Resistant Klebsiella pneumoniae Clones from the Hospital Environment

MG Córdova-Espinoza, S Giono-Cerezo… - Pathogens, 2023 - mdpi.com
Global dispersion, hospital outbreaks, and lineage relationships between emerging
antibiotic-resistant strains such as Klebsiella pneumoniae are of public health interest. This …

[HTML][HTML] Molecular characteristics of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in Japan: Predominance of CTX-M-15 and emergence of …

N Kakuta, R Nakano, A Nakano, Y Suzuki… - International Journal of …, 2020 - Elsevier
Objective To provide data on the molecular characteristics of extended-spectrum β-
lactamase (ESBL)-producing Klebsiella pneumoniae clinical isolates in Japan. Methods A …

Vegetable-derived carbapenemase-producing high-risk Klebsiella pneumoniae ST15 and Acinetobacter baumannii ST2 clones in Japan: coexistence of bla NDM-1 …

AM Soliman, H Nariya, D Tanaka, L Yu… - Applied and …, 2021 - Am Soc Microbiol
This study was conducted to characterize carbapenemase-producing Klebsiella
pneumoniae and Acinetobacter baumannii isolated from fresh vegetables in Japan. Two K …

Genetic analysis of ESBL-producing Klebsiella pneumoniae isolated from UTI patients in Indonesia

S Yamasaki, K Shigemura, K Osawa… - Journal of Infection and …, 2021 - Elsevier
Introduction Extended spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae
is a serious concern for nosocomial infection and the emergence rate in Indonesia is higher …

The determination of gyrA and parC mutations and the prevalence of plasmid-mediated quinolone resistance genes in carbapenem resistant Klebsiella pneumonia …

L Zeng, J Zhang, C Li, Y Fu, Y Zhao, Y Wang… - Infection, Genetics and …, 2020 - Elsevier
Background There is increasing resistance to carbapenems among Klebsiella pneumoniae,
and fluoroquinolones (FQ) are increasingly used to treat infections from extended-spectrum …

First Report of Extended-Spectrum β-Lactamase (blaCTX-M1) and Colistin Resistance Gene mcr-1 in E. coli of Lineage ST648 from Cockroaches in Tunisia

S Landolsi, R Selmi, L Hadjadj… - Microbiology …, 2022 - Am Soc Microbiol
The emergence of multidrug-resistant bacteria has become a major problem. Cockroaches
may play an important role in the spread of those bacteria between the environment and …

Distribution of fluoroquinolone resistance determinants in Carbapenem-resistant Klebsiella pneumoniae clinical isolates associated with bloodstream infections in …

Q Zhan, Y Xu, B Wang, J Yu, X Shen, L Liu, X Cao… - BMC microbiology, 2021 - Springer
Background The rate of fluoroquinolone (FQ) resistance among carbapenem-resistant
Klebsiella pneumoniae (CRKP) is high. The present study aimed to investigate the …

Comparative genetic analysis of the antimicrobial susceptibilities and virulence of hypermucoviscous and non-hypermucoviscous ESBL-producing Klebsiella …

H Tanimoto, K Shigemura, K Osawa, M Kado… - Journal of Microbiology …, 2023 - Elsevier
Abstract Background Hypermucoviscous (HMV) Klebsiella pneumoniae produces large
amounts of capsular polysaccharides, leading to high mortality. Since extended spectrum …

[PDF][PDF] 耐喹诺酮类药物革兰阴性菌的适应性研究

王邦娟, 陈杨, 黄璐璐, 刘理慧, 刘振利, 程古月 - 中国抗生素杂志, 2023 - zgkss.com.cn
随着广谱高效喹诺酮类药物的过度应用, 革兰阴性菌对喹诺酮类药物的耐药率逐年上升,
已严重威胁到人类健康. 革兰阴性菌对喹诺酮类药物的抗性是通过耐药基因突变或者获得外源抗 …