Various circulating substances are involved in blood pressure control in humans and among
these, the effects of serotonin have been well recognized. Its importance in human …

1. The antihypertensive efficacy and tolerability of twice‐daily treatment with the 5‐
hydroxytryptamine antagonist ketanserin were examined in a double‐blind, placebo …

In both acute and long term clinical studies, the antihypertensive effects of the S 2-
serotonergic receptor antagonist ketanserin are more marked in the elderly than in younger …

US5605902A - 5-HT2 receptor antagonist compositions useful in treating venous conditions -
Google Patents US5605902A - 5-HT2 receptor antagonist compositions useful in treating …

Ketanserin is the archetype of a new class of cardiovascular drugs, the 5HT 2 (S 2)
serotonergic receptor antagonists. In humans, ketanserin inhibits serotonin-induced …

The safety and efficacy of ketanserin, a competitive serotonin blocking agent, and
Propranolol were compared in 33 patients with mild to moderate hypertension (sitting …

In a double-blind 3-month study in mild-to-moderate essential hypertensive patients over 50
years of age, ketanserin, a selective S 2-serotoninergic antagonist with additional alpha 1 …

1. This study further investigates the relationship between ketanserin concentration and the
fall in BP in individual hypertensive patients. 2. An integrated kinetic‐dynamic model was …

Commercial heparin preparations differ with regard to structure, molecular weight and
affinity for antithrombin III. They can be separated into fractions with different mean …

Several antihypertensive agents such as thiazide diuretics and some β-blockers have
recently been shown to adversely affect lipid metabolism. Moreover, there is a growing …