From Klebsiella pneumoniae Colonization to Dissemination: An Overview of Studies Implementing Murine Models

L Joseph, T Merciecca, C Forestier, D Balestrino… - Microorganisms, 2021 - mdpi.com
Klebsiella pneumoniae is a Gram-negative pathogen responsible for community-acquired
and nosocomial infections. The strains of this species belong to the opportunistic group …

[HTML][HTML] SARS-CoV-2-indigenous microbiota nexus: does gut microbiota contribute to inflammation and disease severity in COVID-19?

I Chattopadhyay, EM Shankar - Frontiers in cellular and infection …, 2021 - frontiersin.org
Gut microbiome alterations may play a paramount role in determining the clinical outcome of
clinical COVID-19 with underlying comorbid conditions like T2D, cardiovascular disorders …

TPGS-based and S-thanatin functionalized nanorods for overcoming drug resistance in Klebsiella pneumonia

X Wang, X Xu, S Zhang, N Chen, Y Sun, K Ma… - Nature …, 2022 - nature.com
Tigecycline is regarded as the last line of defense to combat multidrug-resistant Klebsiella
pneumoniae. However, increasing utilization has led to rising drug resistance and treatment …

[HTML][HTML] Targeting the Sugary Armor of Klebsiella Species

LPP Patro, T Rathinavelan - Frontiers in cellular and infection …, 2019 - frontiersin.org
The emergence of multidrug-resistant strains of Gram-negative Klebsiella species is an
urgent global threat. The World Health Organization has listed Klebsiella pneumoniae as …

[HTML][HTML] The effect of probiotics on immune responses and their therapeutic application: a new treatment option for multiple sclerosis

B Hashemi, M Abdollahi, S Abbaspour-Aghdam… - Biomedicine & …, 2023 - Elsevier
Multiple sclerosis (MS) is known as a chronic inflammatory disease (CID) that affects the
central nervous system and leads to nerve demyelination. However, the exact cause of MS …

Predatory bacteria as living antibiotics–where are we now?

RJ Atterbury, J Tyson - Microbiology, 2021 - microbiologyresearch.org
Antimicrobial resistance (AMR) is a global health and economic crisis. With too few
antibiotics in development to meet current and anticipated needs, there is a critical need for …

Isolation and Characterization of Klebsiella Phages for Phage Therapy

EM Townsend, L Kelly, L Gannon… - Therapy, Applications …, 2021 - liebertpub.com
Introduction: Klebsiella is a clinically important pathogen causing a variety of antimicrobial
resistant infections in both community and nosocomial settings, particularly pneumonia …

Defining principles that influence antimicrobial peptide activity against capsulated Klebsiella pneumoniae

RM Fleeman, LA Macias… - Proceedings of the …, 2020 - National Acad Sciences
The extracellular polysaccharide capsule of Klebsiella pneumoniae resists penetration by
antimicrobials and protects the bacteria from the innate immune system. Host antimicrobial …

The genomics and cell biology of host-beneficial intracellular infections

JP McCutcheon - Annual Review of Cell and Developmental …, 2021 - annualreviews.org
Microbes gain access to eukaryotic cells as food for bacteria-grazing protists, for host
protection by microbe-killing immune cells, or for microbial benefit when pathogens enter …

Microbiota-derived short-chain fatty acids promote LAMTOR2-mediated immune responses in macrophages

T Wu, H Li, C Su, F Xu, G Yang, K Sun, M Xu, N Lv… - Msystems, 2020 - Am Soc Microbiol
Klebsiella pneumoniae is a common cause of human-pneumonia-derived sepsis with high
morbidity and mortality. The microbiota promotes and maintains host immune homeostasis …