Identifying virulence determinants of multidrug-resistant Klebsiella pneumoniae in Galleria mellonella

S Bruchmann, T Feltwell, J Parkhill… - Pathogens and …, 2021 - academic.oup.com
Infections caused by Klebsiella pneumoniae are a major public health threat. Extensively
drug-resistant and even pan-resistant strains have been reported. Understanding K …

Multidrug-resistant Klebsiella pneumoniae: a retrospective study in Manaus, Brazil

R Nakamura-Silva, L Cerdeira, M Oliveira-Silva… - Archives of …, 2022 - Springer
Klebsiella pneumoniae is an opportunistic pathogen that can cause several infections,
mainly in hospitalised or immunocompromised individuals. The spread of K. pneumoniae …

Immunomodulatory effects of Lactobacillus plantarum on inflammatory response induced by Klebsiella pneumoniae

M Vareille-Delarbre, S Miquel, S Garcin… - Infection and …, 2019 - Am Soc Microbiol
Some respiratory infections have been associated with dysbiosis of the intestinal microbiota.
The underlying mechanism is incompletely understood, but cross talk between the intestinal …

Bacteriophage treatment: critical evaluation of its application on World Health Organization priority pathogens

RK Al-Ishaq, S Skariah, D Büsselberg - Viruses, 2020 - mdpi.com
Bacteriophages represent an effective, natural, and safe strategy against bacterial infections.
Multiple studies have assessed phage therapy's efficacy and safety as an alternative …

Les misérables: a Parallel Between Antimicrobial Resistance and COVID-19 in Underdeveloped and Developing Countries

G Pérez Jorge, IC Rodrigues dos Santos Goes… - Current infectious …, 2022 - Springer
Abstract Purpose of Review The COVID-19 pandemic has been responsible for more than
6.3 million deaths worldwide. During the pandemic, the indiscriminate use of antibiotics has …

Interaction of Klebsiella pneumoniae with tissue macrophages in a mouse infection model and ex-vivo pig organ perfusions: an exploratory investigation

JJ Wanford, RG Hames, D Carreno, Z Jasiunaite… - The Lancet …, 2021 - thelancet.com
Summary Background Hypervirulent Klebsiella pneumoniae (hvKp) strains of capsule type
K1 and K2 cause invasive infections associated with hepatic abscesses, which can be …

Isolation and Molecular Characterization of a Novel Lytic Bacteriophage That Inactivates MDR Klebsiella pneumoniae Strains

VM Balcão, FC Moreli, EC Silva, BG Belline, LF Martins… - Pharmaceutics, 2022 - mdpi.com
The worldwide increase in serious infections caused by multidrug-resistant (MDR) K.
pneumoniae emphasizes the urgent need of new therapeutic strategies for the control of this …

Complexity of Genomic Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae Isolates in Colombia Urges the Reinforcement of Whole Genome …

SY Saavedra, JF Bernal… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an emerging
public health problem. This study explores the specifics of CRKP epidemiology in Colombia …

Outer Membrane Vesicles Derived from Klebsiella pneumoniae Influence the miRNA Expression Profile in Human Bronchial Epithelial BEAS-2B Cells

F Dell'Annunziata, CP Ilisso, C Dell'Aversana, G Greco… - Microorganisms, 2020 - mdpi.com
Klebsiella pneumoniae is an opportunistic pathogen that causes nosocomial and community-
acquired infections. The spread of resistant strains of K. pneumoniae represents a growing …

Phenotypic and genotypic characterization of a Hypervirulent Carbapenem-resistant Klebsiella pneumoniae ST17-KL38 clinical isolate harboring the Carbapenemase …

J He, X Du, X Zeng, RA Moran, W van Schaik… - Microbiology …, 2022 - Am Soc Microbiol
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is a threat to global
public health. We characterized a sequence type 17 (ST17) K. pneumoniae clinical isolate …