Medicinal plants and isolated molecules demonstrating immunomodulation activity as potential alternative therapies for viral diseases including COVID-19
Plants have been extensively studied since ancient times and numerous important chemical
constituents with tremendous therapeutic potential are identified. Attacks of microorganisms …
constituents with tremendous therapeutic potential are identified. Attacks of microorganisms …
The current status of latency reversing agents for HIV-1 remission
A Rodari, G Darcis, CM Van Lint - Annual review of virology, 2021 - annualreviews.org
Combinatory antiretroviral therapy (cART) reduces human immunodeficiency virus type 1
(HIV-1) replication but is not curative because cART interruption almost invariably leads to a …
(HIV-1) replication but is not curative because cART interruption almost invariably leads to a …
Small-molecule modulators targeting toll-like receptors for potential anticancer therapeutics
J Wang, J Zhang, J Wang, X Hu… - Journal of Medicinal …, 2023 - ACS Publications
Toll-like receptors (TLRs) are key components of the innate immune system and serve as a
crucial link between innate and acquired immunity. In addition to immune function, TLRs are …
crucial link between innate and acquired immunity. In addition to immune function, TLRs are …
Toll‐Like Receptor‐Based Strategies for Cancer Immunotherapy
S Pahlavanneshan, A Sayadmanesh… - Journal of …, 2021 - Wiley Online Library
Toll‐like receptors (TLRs) are expressed and play multiple functional roles in a variety of
immune cell types involved in tumor immunity. There are plenty of data on the …
immune cell types involved in tumor immunity. There are plenty of data on the …
Recent progress in stimuli-responsive nanosystems for inducing immunogenic cell death
Low immunogenicity and immunosuppressive tumor microenvironments are major hurdles
in the application of cancer immunotherapy. To date, several immunogenic cell death (ICD) …
in the application of cancer immunotherapy. To date, several immunogenic cell death (ICD) …
The role of toll‐like receptor 4 (TLR4) in cancer progression: A possible therapeutic target?
The toll‐like receptor (TLR) family consists of vital receptors responsible for pattern
recognition in innate immunity, making them the core proteins involved in pathogen …
recognition in innate immunity, making them the core proteins involved in pathogen …
The role of toll-like receptor agonists and their nanomedicines for tumor immunotherapy
L Huang, X Ge, Y Liu, H Li, Z Zhang - Pharmaceutics, 2022 - mdpi.com
Toll-like receptors (TLRs) are a class of pattern recognition receptors that play a critical role
in innate and adaptive immunity. Toll-like receptor agonists (TLRa) as vaccine adjuvant …
in innate and adaptive immunity. Toll-like receptor agonists (TLRa) as vaccine adjuvant …
[HTML][HTML] Neuroinflammation in retinitis pigmentosa: Therapies targeting the innate immune system
L Zhao, C Hou, N Yan - Frontiers in Immunology, 2022 - frontiersin.org
Retinitis pigmentosa (RP) is an important cause of irreversible blindness worldwide and
lacks effective treatment strategies. Although mutations are the primary cause of RP …
lacks effective treatment strategies. Although mutations are the primary cause of RP …
Application and prospect of targeting innate immune sensors in the treatment of autoimmune diseases
J Liu, H Zhang, Y Su, B Zhang - Cell & Bioscience, 2022 - Springer
Dysregulation of auto-reactive T cells and autoantibody-producing B cells and excessive
inflammation are responsible for the occurrence and development of autoimmune diseases …
inflammation are responsible for the occurrence and development of autoimmune diseases …
Structural evolution and translational potential for agonists and antagonists of endosomal toll-like receptors
Toll-like receptors (TLRs) are members of a large family of evolutionarily conserved pattern
recognition receptors (PRRs), which serve as key components of the innate immune system …
recognition receptors (PRRs), which serve as key components of the innate immune system …