[HTML][HTML] Dynamic lipid turnover in photoreceptors and retinal pigment epithelium throughout life

D Lewandowski, CL Sander, A Tworak, F Gao… - Progress in retinal and …, 2022 - Elsevier
The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Eryptosis: programmed death of nucleus-free, iron-filled blood cells

P Dreischer, M Duszenko, J Stein, T Wieder - Cells, 2022 - mdpi.com
Human erythrocytes are organelle-free cells packaged with iron-containing hemoglobin,
specializing in the transport of oxygen. With a total number of approximately 25 trillion cells …

Role of ceramides in the pathogenesis of diabetes mellitus and its complications

N Mandal, R Grambergs, K Mondal, SK Basu… - Journal of Diabetes and …, 2021 - Elsevier
Diabetes mellitus (DM) is a systemic metabolic disease that affects 463 million adults
worldwide and is a leading cause of cardiovascular disease, blindness, nephropathy …

Very long-chain saturated fatty acids and diabetes and cardiovascular disease

RN Lemaitre, IB King - Current opinion in lipidology, 2022 - journals.lww.com
Very long-chain saturated fatty acids and diabetes and cardi... : Current Opinion in Lipidology
Very long-chain saturated fatty acids and diabetes and cardiovascular disease : Current …

Advances in determining signaling mechanisms of ceramide and role in disease

JL Stith, FN Velazquez, LM Obeid - Journal of lipid research, 2019 - ASBMB
Ceramide is a critical bioactive lipid involved in diverse cellular processes. It has been
proposed to regulate cellular processes by influencing membrane properties and by directly …

Sphingolipids as critical players in retinal physiology and pathology

MV Simon, SK Basu, B Qaladize, R Grambergs… - Journal of lipid …, 2021 - ASBMB
Sphingolipids have emerged as bioactive lipids involved in the regulation of many
physiological and pathological processes. In the retina, they have been established to …

Sphingolipids as emerging mediators in retina degeneration

MV Simón, FH Prado Spalm, MS Vera… - Frontiers in cellular …, 2019 - frontiersin.org
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and
ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular …

Microglia modulate stable wakefulness via the thalamic reticular nucleus in mice

H Liu, X Wang, L Chen, L Chen, SE Tsirka, S Ge… - Nature …, 2021 - nature.com
Microglia are important for brain homeostasis and immunity, but their role in regulating
vigilance remains unclear. We employed genetic, physiological, and metabolomic methods …

Inimitable impacts of ceramides on lipid rafts formed in artificial and natural cell membranes

M Kinoshita, N Matsumori - Membranes, 2022 - mdpi.com
Ceramide is the simplest precursor of sphingolipids and is involved in a variety of biological
functions ranging from apoptosis to the immune responses. Although ceramide is a minor …

Coronary event risk test (CERT) as a risk predictor for the 10-year clinical outcome of patients with peripheral artery disease

A Leiherer, A Muendlein, CH Saely, K Geiger… - Journal of Clinical …, 2023 - mdpi.com
(1) Background: Ceramides are a new kind of lipid biomarker and have already been
demonstrated to be valuable risk predictors in coronary patients. Patients with peripheral …