Epidemiology of esophageal squamous cell carcinoma

CC Abnet, M Arnold, WQ Wei - Gastroenterology, 2018 - Elsevier
Esophageal squamous cell carcinoma (ESCC) accounts for about 90% of the 456,000
incident esophageal cancers each year. Regions of high incidence include Eastern to …

Gastrointestinal cancers in China, the USA, and Europe

Y Xie, L Shi, X He, Y Luo - Gastroenterology report, 2021 - academic.oup.com
Gastrointestinal (GI) cancers, including colorectal cancer, gastric cancer, and esophageal
cancer, are a major medical and economic burden worldwide and have the largest number …

Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence

S Moody, S Senkin, SMA Islam, J Wang… - Nature Genetics, 2021 - nature.com
Esophageal squamous cell carcinoma (ESCC) shows remarkable variation in incidence that
is not fully explained by known lifestyle and environmental risk factors. It has been …

The critical roles of somatic mutations and environmental tumor-promoting agents in cancer risk

A Balmain - Nature genetics, 2020 - nature.com
Cancer is driven by genomic mutations in 'cancer driver'genes, which have essential roles in
tumor development. These mutations may be caused by exposure to mutagens in the …

Cancer situation in China: what does the China cancer map indicate from the first national death survey to the latest cancer registration?

R Feng, Q Su, X Huang, T Basnet, X Xu… - Cancer …, 2023 - Wiley Online Library
Background Over the past four decades, the Chinese government has conducted three
surveys on the distribution of causes of death and built cancer registration. In order to shine …

Individual and combined effects of environmental risk factors for esophageal cancer based on results from the Golestan Cohort Study

M Sheikh, H Poustchi, A Pourshams, A Etemadi… - Gastroenterology, 2019 - Elsevier
Background & Aims Northeast Iran has one of the highest reported rates of esophageal
squamous cell carcinoma (ESCC) worldwide. Decades of investigations in this region have …

Identifying novel causes of cancers to enhance cancer prevention: new strategies are needed

P Brennan, G Davey-Smith - JNCI: Journal of the National …, 2022 - academic.oup.com
The burden of cancer from a clinical, societal, and economic viewpoint continues to increase
in all parts of the world, along with much debate regarding how to confront this. Projected …

[HTML][HTML] Extracellular vesicle IL-32 promotes the M2 macrophage polarization and metastasis of esophageal squamous cell carcinoma via FAK/STAT3 pathway

Y Sun, Y Qian, C Chen, H Wang, X Zhou… - Journal of Experimental …, 2022 - Springer
Background Metastasis is the leading cause of mortality in human cancers, including
esophageal squamous cell carcinoma (ESCC). As a pro-inflammatory cytokine, IL-32 was …

Hafnium-based metal–organic framework nanoparticles as a radiosensitizer to improve radiotherapy efficacy in esophageal cancer

W Zhou, Z Liu, N Wang, X Chen, X Sun, Y Cheng - ACS omega, 2022 - ACS Publications
Radiotherapy is one of the most widely used clinical treatments for tumors, but it faces
limitations, such as poor X-ray retention at the tumor site. The use of radiosensitizers …

The 3-deoxysappanchalcone induces ROS-mediated apoptosis and cell cycle arrest via JNK/p38 MAPKs signaling pathway in human esophageal cancer cells

AW Kwak, MJ Lee, MH Lee, G Yoon, SS Cho, JI Chae… - Phytomedicine, 2021 - Elsevier
Abstract Background The 3-deoxysappanchalcone (3-DSC), a chemical separated from
Caesalpinia sappan L, has been substantiated to display anti-inflammatory, anti-influenza …