Esophageal cancer-derived extracellular vesicle miR-21-5p contributes to EMT of ESCC cells by disorganizing macrophage polarization

J Song, P Yang, X Li, X Zhu, M Liu, X Duan, R Liu - Cancers, 2021 - mdpi.com
Simple Summary Macrophage polarization-associated extracellular vesicles (EVs) play
crucial roles in tumor progression. The role of miR-21-5p in EVs during esophageal …

IGF2BP2-induced circRUNX1 facilitates the growth and metastasis of esophageal squamous cell carcinoma through miR-449b-5p/FOXP3 axis

C Wang, M Zhou, P Zhu, C Ju, J Sheng, D Du… - Journal of Experimental …, 2022 - Springer
Background Esophageal squamous cell carcinoma (ESCC) is one of the most common
digestive malignancies with relatively high morbidity and mortality. Emerging evidence …

International trends in oesophageal cancer survival by histological subtype between 1995 and 2014

E Morgan, I Soerjomataram, AT Gavin, MJ Rutherford… - Gut, 2021 - gut.bmj.com
Introduction Survival from oesophageal cancer remains poor, even across high-income
countries. Ongoing changes in the epidemiology of the disease highlight the need for …

Exposure to polycyclic aromatic hydrocarbons, volatile organic compounds, and tobacco-specific nitrosamines and incidence of esophageal cancer

A Etemadi, H Poustchi, CM Chang… - JNCI: Journal of the …, 2024 - academic.oup.com
Background Studying carcinogens in tobacco and nontobacco sources may be key to
understanding the pathogenesis and geographic distribution of esophageal cancer …

Epidemiological landscape of esophageal cancer in Asia: results from GLOBOCAN 2020

H Zhu, Z Wang, B Deng, M Mo, H Wang… - Thoracic …, 2023 - Wiley Online Library
Background Esophageal cancer (EC) is a global health problem. Asia represents a huge
burden of EC globally, and incidence and mortality vary considerably across different Asian …

Garcinol inhibits esophageal cancer metastasis by suppressing the p300 and TGF-β1 signaling pathways

J Wang, M Wu, D Zheng, H Zhang, Y Lv… - Acta Pharmacologica …, 2020 - nature.com
Metastasis causes the main lethality in esophageal cancer patient. Garcinol, a natural
compound extracted from Gambogic genera, is a histone acetyltransferase (HAT) inhibitor …

[HTML][HTML] Global, regional, and national lifetime risks of developing and dying from gastrointestinal cancers in 185 countries: a population-based systematic analysis of …

S Wang, R Zheng, J Li, H Zeng, L Li, R Chen… - The Lancet …, 2024 - thelancet.com
Background Gastrointestinal cancers account for a quarter of the global cancer incidence
and a third of cancer-related deaths. We sought to estimate the lifetime risks of developing …

The African esophageal cancer consortium: a call to action

K Van Loon, MM Mwachiro, CC Abnet… - Journal of Global …, 2018 - ascopubs.org
Esophageal cancer is the eighth most common cancer worldwide and the sixth most
common cause of cancer-related death; however, worldwide incidence and mortality rates …

[HTML][HTML] Comparative genomic analysis of esophageal squamous cell carcinoma and adenocarcinoma: New opportunities towards molecularly targeted therapy

X Zhang, Y Wang, L Meng - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Esophageal cancer is one of the most lethal cancers worldwide because of its rapid
progression and poor prognosis. Esophageal squamous cell carcinoma (ESCC) and …

Tumor-derived EV-encapsulated miR-181b-5p induces angiogenesis to foster tumorigenesis and metastasis of ESCC

Y Wang, J Lu, L Chen, H Bian, J Hu, D Li, C Xia… - … Therapy-Nucleic Acids, 2020 - cell.com
Pathological angiogenesis is necessary for tumor development and metastasis. Tumor-
derived extracellular vesicles (EVs) play an important role in mediating the crosstalk …