Humoral immunity in atherosclerosis and myocardial infarction: from B cells to antibodies
Immune mechanisms are critically involved in the pathogenesis of atherosclerosis and its
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …
The why and how of adaptive immune responses in ischemic cardiovascular disease
Atherosclerotic cardiovascular disease is a major cause of disability and death worldwide.
Most therapeutic approaches target traditional risk factors but ignore the fundamental role of …
Most therapeutic approaches target traditional risk factors but ignore the fundamental role of …
Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization
F Fasolo, H Jin, G Winski, E Chernogubova, J Pauli… - Circulation, 2021 - Am Heart Assoc
Background: Long noncoding RNAs (lncRNAs) are important regulators of biological
processes involved in vascular tissue homeostasis and disease development. The present …
processes involved in vascular tissue homeostasis and disease development. The present …
The impact of type 2 immunity and allergic diseases in atherosclerosis
N Fernández‐Gallego, R Castillo‐González… - Allergy, 2022 - Wiley Online Library
Allergic diseases are allergen‐induced immunological disorders characterized by the
development of type 2 immunity and IgE responses. The prevalence of allergic diseases has …
development of type 2 immunity and IgE responses. The prevalence of allergic diseases has …
Shenxiang Suhe pill improves cardiac function through modulating gut microbiota and serum metabolites in rats after acute myocardial infarction
X Zhong, J Yan, X Wei, T Xie, Z Zhang… - Pharmaceutical …, 2024 - Taylor & Francis
Abstract Context Shenxiang Suhe pill (SXSH), a traditional Chinese medicine, is clinically
effective against coronary heart disease, but the mechanism of cardiac-protective function is …
effective against coronary heart disease, but the mechanism of cardiac-protective function is …
Role of Antibodies and Their Specificities in Atherosclerotic Cardiovascular Disease
J Deroissart, CJ Binder, F Porsch - … , Thrombosis, and Vascular …, 2024 - ahajournals.org
Atherosclerosis is a lipid-driven chronic inflammatory disease that is modulated by innate
and adaptive immunity including humoral immunity. Importantly, antibody alterations …
and adaptive immunity including humoral immunity. Importantly, antibody alterations …
Lipoprotein (a) and Immunity
OI Afanasieva, TI Arefieva, MV Ezhov, SN Pokrovsky - Lipoprotein (a), 2023 - Springer
Abstract Elevated lipoprotein (a)[Lp (a)] is a valuable risk factor for development of
atherosclerotic cardiovascular diseases (ASCVD). Within this chapter, we discuss the …
atherosclerotic cardiovascular diseases (ASCVD). Within this chapter, we discuss the …
Mini review: Structure and function of nematode phosphorylcholine-containing glycoconjugates
G Buitrago, J Duncombe-Moore, MM Harnett… - Frontiers in Tropical …, 2021 - frontiersin.org
An unusual aspect of the biology of nematodes is the covalent attachment of
phosphorylcholine (PC) to carbohydrate in glycoconjugates. Investigation of the structure of …
phosphorylcholine (PC) to carbohydrate in glycoconjugates. Investigation of the structure of …
Phosphorylcholine monoclonal antibody therapy decreases intraplaque angiogenesis and intraplaque hemorrhage in murine vein grafts
F Baganha, TJ Sluiter, RCM de Jong… - International Journal of …, 2022 - mdpi.com
Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in
atherosclerosis, due to its atherogenic and proinflammatory effects. PC can be cleared by …
atherosclerosis, due to its atherogenic and proinflammatory effects. PC can be cleared by …
Landscape of circulating metabolic fingerprinting for keloid
Y Hu, X Zhou, L Chen, R Li, S Jin, L Liu, M Ju… - Frontiers in …, 2022 - frontiersin.org
Background Keloids are a fibroproliferative disease characterized by unsatisfactory
therapeutic effects and a high recurrence rate. Objective This study aimed to investigate …
therapeutic effects and a high recurrence rate. Objective This study aimed to investigate …