The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along
with mounting evidence of clinically important sex and gender differences. T2DM is more …

Background: Fetal macrosomia, defined as a birth weight≥ 4,000 g, may affect 12% of
newborns of normal women and 15-45% of newborns of women with gestational diabetes …

Environmental exposures, psychosocial stressors and nutrition are all potentially important
influences that may impact health outcomes directly or via interactions with the genome or …

Context Accurate methods for early gestational diabetes mellitus (GDM)(during the first
trimester of pregnancy) prediction in Chinese and other populations are lacking. Objectives …

BACKGROUND A defining feature of sexual reproduction is the transmission of genomic
information from both parents to the offspring. There is now compelling evidence that the …

The global pandemic of obesity and type 2 diabetes is often causally linked to marked
changes in diet and lifestyle; namely marked increases in dietary intakes of high energy …

The effects of diabetes mellitus include long-term damages, dysfunctions, and failures of
various organs. An important complication of diabetes is the disturbance in the male …

Fetal metabolic programming caused by the adverse intrauterine environment can induce
metabolic syndrome in adult offspring. Adverse intrauterine environment introduces fetal …

The type 2 diabetes epidemic and one of its predisposing factors, obesity, are major
influences on global health and economic burden. It is accepted that genetics and the …

BACKGROUND The concept of developmental programming suggests that the early life
environment influences offspring characteristics in later life, including the propensity to …