Neutrophil extracellular traps mediate deep vein thrombosis: from mechanism to therapy

M Yao, J Ma, D Wu, C Fang, Z Wang, T Guo… - Frontiers in …, 2023 - frontiersin.org
Deep venous thrombosis (DVT) is a part of venous thromboembolism (VTE) that clinically
manifests as swelling and pain in the lower limbs. The most serious clinical complication of …

Inflammation and immunity in the pathogenesis of hypoxic pulmonary hypertension

Y Ye, Q Xu, T Wuren - Frontiers in Immunology, 2023 - frontiersin.org
Hypoxic pulmonary hypertension (HPH) is a complicated vascular disorder characterized by
diverse mechanisms that lead to elevated blood pressure in pulmonary circulation. Recent …

The perspectives of NETosis on the progression of obesity and obesity-related diseases: mechanisms and applications

J Li, L Yin, S Chen, Z Li, J Ding, J Wu… - Frontiers in Cell and …, 2023 - frontiersin.org
Obesity is a disease commonly associated with urbanization and can also be characterized
as a systemic, chronic metabolic condition resulting from an imbalance between energy …

Airway delivery of Streptococcus salivarius is sufficient to induce experimental pulmonary hypertension in rats

C Zhang, T Zhang, Y Xing, W Lu, J Chen… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose The causal relationship between altered host microbiome
composition, especially the respiratory tract microbiome, and the occurrence of pulmonary …

Identification of JPX-RABEP1 Pair as an Immune-Related Biomarker and Therapeutic Target in Pulmonary Arterial Hypertension by Bioinformatics and Experimental …

Q Gong, Z Hu, Q Jin, Y Yan, Y Liu, J He… - International Journal of …, 2022 - mdpi.com
Pulmonary arterial hypertension (PAH) is a pulmonary vascular disease characterized by
pulmonary vascular remodeling and right heart enlargement the pathogenesis of PAH is …

A promising frontier: targeting NETs for stroke treatment breakthroughs

H Fang, Y Bo, Z Hao, G Mang, J Jin, H Wang - Cell Communication and …, 2024 - Springer
Stroke is a prevalent global acute cerebrovascular condition, with ischaemic stroke being
the most frequently occurring type. After a stroke, neutrophils accumulate in the brain and …

Serum ASGR2 level: an efficacy biomarker for balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension

WJ Xu, S Wang, QH Zhao, JY Xu, XY Hu… - Frontiers in …, 2024 - frontiersin.org
Background This study aimed to employ plasma proteomics to investigate the molecular
changes, pathway alterations, and potential novel biochemical markers associated with …

Neutrophils mediate pulmonary artery thrombosis in situ

O Porembskaya, V Zinserling, V Tomson… - International Journal of …, 2022 - mdpi.com
Pulmonary embolism is a life-threatening condition, which can result in respiratory
insufficiency and death. Blood clots occluding branches of the pulmonary artery (PA) are …

Role of the Systemic Inflammatory Response Index in Predicting Disease Severity and Prognosis in Idiopathic Pulmonary Arterial Hypertension

L Gao, S Zhang, Z Zhao, Q Zhao, T Yang… - Journal of …, 2024 - Taylor & Francis
Introduction Mounting evidence indicates a possible connection between the systemic
inflammatory response index (SIRI) and the prognosis of heart failure, but its role in …

Pulmonary Hypertension and the Risk of 30-Day Postoperative Pulmonary Complications after Gastrointestinal Surgical or Endoscopic Procedures: A Retrospective …

Y Tatsuoka, ZJ Carr, S Jayakumar, HM Lin… - Journal of Clinical …, 2024 - mdpi.com
Background: Pulmonary hypertension (PH) patients are at higher risk of postoperative
complications. We analyzed the association of PH with 30-day postoperative pulmonary …