Learning Objectives Contrast the current strengths and limitations of the three main slide-
based techniques (IHC, FISH, and CISH) currently in clinical use for testing breast cancer …

Male breast cancer is a rare disease, accounting for less than 1% of all breast cancer
diagnoses worldwide. Most data on male breast cancer comes from small single-institution …

Background The causes, optimal treatments, and medical/psychosocial sequelae of breast
cancer in men are poorly understood. Design A systematic review of the English language …

Abstract Learning Objectives After completing this course, the reader will be able to: Define
the historical background and biological basis of the discovery of the HER-2/neu gene and …

The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb gene
family, encodes a transmembrane tyrosine kinase receptor that has been linked to prognosis …

Male breast cancer accounts for around 1% of all breast cancer cases, but the incidence has
increased over the past 25years. The rarity of this entity precludes prospective randomized …

Background The overall incidence of male breast cancer is around 1% of all breast cancers
and is on the rise. In this review we aim to present various aspects of male breast cancer …

BACKGROUND. The incidence of male breast cancer (MBC) continues to rise. The Veterans
Affairs (VA) Central Cancer Registry (VACCR) provides a unique source for the study of …

Male breast cancer is rare. Median age at diagnosis is~ 65 years, and> 35% of male breast
cancers occur in elderly men. Retroareolar lump is the most frequent symptom, and 25–30 …

Background Male breast cancer accounts for less than 1% of all breast cancers, yet males
have a worse prognosis than females with breast cancer. Methods Using the 1988–2003 …