Eclampsia in the 21st century

MF Bartal, BM Sibai - American journal of obstetrics and gynecology, 2022 - Elsevier
The reported incidence of eclampsia is 1.6 to 10 per 10,000 deliveries in developed
countries, whereas it is 50 to 151 per 10,000 deliveries in developing countries. In addition …

Sex-and gender-based pharmacological response to drugs

F Mauvais-Jarvis, HK Berthold, I Campesi… - Pharmacological …, 2021 - ASPET
In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences
of biologic sex produces different in vivo environments for male and female cells. We dissect …

Hypertensive disorders of pregnancy and cognitive impairment: a prospective cohort study

MC Adank, RF Hussainali, LC Oosterveer, MA Ikram… - Neurology, 2021 - AAN Enterprises
Objective To determine the association between hypertensive disorders of pregnancy (HDP)
and cognitive impairment 15 years after pregnancy, we measured cognitive performance in …

Preeclampsia history and postpartum risk of cerebrovascular disease and cognitive impairment: Potential mechanisms

AG Beckett, MD McFadden, JP Warrington - Frontiers in Physiology, 2023 - frontiersin.org
Hypertensive disorders of pregnancy such as preeclampsia, eclampsia, superimposed
preeclampsia, and gestational hypertension are major causes of fetal and maternal …

Maternal stroke: a call for action

IY Elgendy, S Bukhari, AF Barakat, CJ Pepine… - Circulation, 2021 - Am Heart Assoc
Maternal mortality rates have been steadily increasing in the United States, and
cardiovascular mortality is the leading cause of death among pregnant and postpartum …

Acute intracranial hypertension during pregnancy: special considerations and management adjustments

DA Godoy, C Robba, WS Paiva, AA Rabinstein - Neurocritical care, 2022 - Springer
Pregnancy is associated with a number of pathophysiological changes (including
modification of vascular resistance, increased vascular permeability, and coagulative …

Advanced maternal age impairs uterine artery adaptations to pregnancy in rats

AL Wooldridge, M Pasha, P Chitrakar… - International Journal of …, 2022 - mdpi.com
Advanced maternal age (≥ 35 years) is associated with pregnancy complications. Aging
impairs vascular reactivity and increases vascular stiffness. We hypothesized that uterine …

Brain vascular dysfunction in mothers and their children exposed to preeclampsia

C Escudero, E Kupka, B Ibañez, H Sandoval… - …, 2023 - Am Heart Assoc
Preeclampsia is a maternal syndrome characterized by the new onset of hypertension and
proteinuria after 20 weeks of gestation associated with multisystemic complications …

Posterior reversible leucoencephalopathy syndrome: Case series, comments, and diagnostic dilemma

J Chaudhuri, S Basu, MK Roy… - Current Neurology and …, 2023 - Springer
Abstract Purpose of Review To report a series of patients with clinical and radiological
features suggestive of posterior reversible encephalopathy syndrome (PRES) related to …

Maternal microvascular dysfunction during preeclamptic pregnancy

AE Stanhewicz, VR Nuckols, GL Pierce - Clinical Science, 2021 - portlandpress.com
Preeclampsia is a hypertensive disorder of pregnancy effecting∼ 5–8% of pregnancies in
the United States, and∼ 8 million pregnancies worldwide. Preeclampsia is clinically …