Tumor microenvironment-mediated immune tolerance in development and treatment of gastric cancer

Y Liu, C Li, Y Lu, C Liu, W Yang - Frontiers in Immunology, 2022 - frontiersin.org
Tumor microenvironment is the general term for all non-cancer components and their
metabolites in tumor tissue. These components include the extracellular matrix, fibroblasts …

A comprehensive review of the classical prescription Yiguan Jian: Phytochemistry, quality control, clinical applications, pharmacology, and safety profile

C Lu, S Zhang, S San Lei, D Wang, B Peng… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Yiguan Jian (YGJ) is a classical prescription,
which employs 6 kinds of medicinal herbs including Rehmanniae Radix, Lycii Fructus …

[HTML][HTML] Rgl-exomiR-7972, a novel plant exosomal microRNA derived from fresh Rehmanniae Radix, ameliorated lipopolysaccharide-induced acute lung injury and …

FS Qiu, JF Wang, MY Guo, XJ Li, CY Shi, F Wu… - Biomedicine & …, 2023 - Elsevier
Plant-derived exosome-like nanoparticles (ELNs) have been proposed as a novel
therapeutic tool for preventing human diseases. However, the number of well-verified plant …

Piper nigrum extract suppresses tumor growth and enhances the antitumor immune response in murine models of breast cancer and melanoma

P Lasso, L Rojas, C Arévalo, C Urueña… - Cancer Immunology …, 2023 - Springer
Although the antitumor effect of P. nigrum has been widely studied, research related to its
possible immunomodulatory effects is relatively scarce. Here, the antitumor and …

[HTML][HTML] Myc oncogene: a druggable target for treating cancers with natural products

KI Chan, S Zhang, G Li, Y Xu, L Cui, Y Wang… - Aging and …, 2024 - ncbi.nlm.nih.gov
Various diseases, including cancers, age-associated disorders, and acute liver failure, have
been linked to the oncogene, MYC. Animal testing and clinical trials have shown that …

[HTML][HTML] A review on the application, phytochemistry and pharmacology of Polygonatum odoratum, an edible medicinal plant

J Bi, H Fang, J Zhang, L Lu, X Gu, Y Zheng - Journal of Future Foods, 2023 - Elsevier
Polygonatum odoratum is distributed in several countries around the world as a medicinal
and dual-use plant, and its rhizomes are used in China as a traditional Chinese medicine …

Glycyrrhizae Radix et Rhizoma: The popular occurrence of herbal medicine applied in classical prescriptions

L He, Q Kang, Y Zhang, M Chen, Z Wang… - Phytotherapy …, 2023 - Wiley Online Library
Abstract Glycyrrhizae Radix et Rhizoma is a well‐known herbal medicine with a wide range
of pharmacological functions that has been used throughout Chinese history. This review …

Contamination and health risk assessment of multiple mycotoxins in edible and medicinal plants

Y Zhang, F Kuang, C Liu, K Ma, T Liu, M Zhao, G Lv… - Toxins, 2023 - mdpi.com
Edible and medicinal plants (EMPs) are widely used but are easily infected by harmful fungi
which produce mycotoxins. Herein, 127 samples from 11 provinces were collected to …

Exploring the active components and potential mechanisms of Rosa roxburghii Tratt in treating type 2 diabetes mellitus based on UPLC-Q-exactive Orbitrap/MS and …

C Shen, Y Wang, H Zhang, W Li, W Chen, M Kuang… - Chinese Medicine, 2023 - Springer
Background Type 2 diabetes mellitus (T2DM) is a global disease with growing prevalence
that is difficult to cure. Rosa roxburghii Tratt is an edible and medicinal plant, and modern …

A Novel Bromophenol Compound from Leathesia nana Inhibits Breast Cancer in a Direct Tumor Killing and Immunotherapy Manner

R Sun, M Zhang, B Li, S Jiang, W Yu, L Yang, Y Han… - Molecules, 2023 - mdpi.com
Considering the resistance and toxicity of traditional chemotherapeutic drugs, seeking
potential candidate for treating breast cancer effectively is a clinical problem that should be …