Lipids, lipid-lowering therapy, and neuropathy: a narrative review
ABSTRACT Statins, or 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are the
mainstay of treatment for hypercholesterolemia as they effectively reduce LDL-C levels and …
mainstay of treatment for hypercholesterolemia as they effectively reduce LDL-C levels and …
Efficacy and safety of PCSK9 monoclonal antibodies
Z Iqbal, S Dhage, JB Mohamad… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are novel
drugs that have been developed since the discovery of the PCSK9 protein in 2003. In …
drugs that have been developed since the discovery of the PCSK9 protein in 2003. In …
Efficacy and safety of PCSK9 monoclonal antibodies in patients with Diabetes
Purpose Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are novel drugs
that have proven efficacy in improving cardiovascular outcomes. Roles for the PCSK9 …
that have proven efficacy in improving cardiovascular outcomes. Roles for the PCSK9 …
Rationale and design of a randomised double-blind 2× 2 factorial trial comparing the effect of a 3-month intensive statin and antiplatelet therapy for patients with acute …
Y Gao, Y Pan, S Han, W Chen, J Jing… - Stroke and Vascular …, 2023 - svn.bmj.com
Background It remains unclear if intensive antiplatelet and statin treatments begun within 24–
72 hours of cerebral ischaemic events from intracranial or extracranial atherosclerosis is …
72 hours of cerebral ischaemic events from intracranial or extracranial atherosclerosis is …
Nutrition-related diseases and cardiovascular mortality in American society: national health and nutrition examination study, 1999–2006
W Chen, S Shi, J Tu, L Liao, Y Liao, K Chen, L Chen… - BMC Public Health, 2022 - Springer
Background Despite many significant advances in treatment and management,
cardiovascular disease remains the main cause of the global disease burden. Nutrition …
cardiovascular disease remains the main cause of the global disease burden. Nutrition …
Quantitative evaluation of statin effectiveness versus intolerance and strategies for management of intolerance
Background and aims There is disquiet about statin effectiveness and side effects in both the
medical and lay media. Methods We searched the literature for reports on the incidence of …
medical and lay media. Methods We searched the literature for reports on the incidence of …
Lipid management beyond the guidelines
JG Robinson - Progress in cardiovascular diseases, 2019 - Elsevier
The 2018 AHA/ACC cholesterol guideline builds on the 2013 ACC/AHA cholesterol
guideline statin recommendations to provide more detailed recommendations for the use of …
guideline statin recommendations to provide more detailed recommendations for the use of …
The impact of early in-hospital use of PCSK9 inhibitors on cardiovascular outcomes in acute coronary syndrome patients: A systematic review and meta-analysis
D Yifan, M Yue, Z Yubin, G Jiapei, S Xu… - International Journal of …, 2024 - Elsevier
Objective To explore the safety and assess the cardiovascular impact of early in-hospital
administration of PCSK9 inhibitors in patients with acute coronary syndrome (ACS). Methods …
administration of PCSK9 inhibitors in patients with acute coronary syndrome (ACS). Methods …
Melatonin may increase anticancer potential of pleiotropic drugs
Melatonin (N-acetyl-5-methoxytryptamine) is not only a pineal hormone, but also an
ubiquitary molecule present in plants and part of our diet. Numerous preclinical and some …
ubiquitary molecule present in plants and part of our diet. Numerous preclinical and some …
Lipid management in ischaemic stroke or transient ischaemic attack in China: result from China National Stroke Registry III
YY Xu, WQ Chen, MX Wang, YS Pan, ZX Li, LP Liu… - BMJ open, 2023 - bmjopen.bmj.com
Objectives The aims of the study were to assess the management of low-density lipoprotein
cholesterol (LDL-C) and the goal achievement, as well as to investigate the association …
cholesterol (LDL-C) and the goal achievement, as well as to investigate the association …