Histidine as a key modulator of molecular self-assembly: Peptide-based supramolecular materials inspired by biological systems

Y Chen, K Tao, W Ji, VB Kumar, S Rencus-Lazar… - Materials Today, 2022 - Elsevier
Histidine, a versatile proteinogenic amino acid, plays a broad range of roles in all living
organisms and behaves as a key mediator of the interactions of biomolecules with inorganic …

(Macro) molecular self-assembly for hydrogel drug delivery

MJ Webber, ET Pashuck - Advanced drug delivery reviews, 2021 - Elsevier
Hydrogels prepared via self-assembly offer scalable and tunable platforms for drug delivery
applications. Molecular-scale self-assembly leverages an interplay of attractive and …

Supramolecular hydrogels: Design strategies and contemporary biomedical applications

J Omar, D Ponsford, CA Dreiss… - Chemistry–An Asian …, 2022 - Wiley Online Library
Self‐assembly of supramolecular hydrogels is driven by dynamic, non‐covalent interactions
between molecules. Considerable research effort has been exerted to fabricate and …

[HTML][HTML] Rational design of smart hydrogels for biomedical applications

Y Zhang, Y Huang - Frontiers in Chemistry, 2021 - frontiersin.org
Hydrogels are polymeric three-dimensional network structures with high water content. Due
to their superior biocompatibility and low toxicity, hydrogels play a significant role in the …

[HTML][HTML] Rational design of peptide-based smart hydrogels for therapeutic applications

S Das, D Das - Frontiers in Chemistry, 2021 - frontiersin.org
Peptide-based hydrogels have captivated remarkable attention in recent times and serve as
an excellent platform for biomedical applications owing to the impressive amalgamation of …

Temperature-responsive supramolecular hydrogels

S Xian, MJ Webber - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Hydrogels comprise a class of soft materials which are extremely useful in a number of
contexts, for example as matrix-mimetic biomaterials for applications in regenerative …

Multifunctional self-assembled peptide hydrogels for biomedical applications

M Sedighi, N Shrestha, Z Mahmoudi, Z Khademi… - Polymers, 2023 - mdpi.com
Self-assembly is a growth mechanism in nature to apply local interactions forming a
minimum energy structure. Currently, self-assembled materials are considered for …

Self-assembling peptide hydrogels for the stabilization and sustained release of active Chondroitinase ABC in vitro and in spinal cord injuries

A Raspa, L Carminati, R Pugliese, F Fontana… - Journal of controlled …, 2021 - Elsevier
Activated microglia/macrophages infiltration, astrocyte migration, and increased production
of inhibitory chondroitin sulfate proteoglycans (CSPGs) are standard harmful events taking …

Self-assembly hydrogels of therapeutic agents for local drug delivery

J Zheng, X Song, Z Yang, C Yin, W Luo, C Yin… - Journal of Controlled …, 2022 - Elsevier
Advanced drug delivery systems are of vital importance to enhance therapeutic efficacy.
Among various recently developed formulations, self-assembling hydrogels composed of …

Glucose-fueled peptide assembly: glucagon delivery via enzymatic actuation

S Yu, S Xian, Z Ye, I Pramudya… - Journal of the American …, 2021 - ACS Publications
Nature achieves remarkable function from the formation of transient, nonequilibrium
materials realized through continuous energy input. The role of enzymes in catalyzing …