Purpose: He Tangata Kei Tua, a relationship model for biobanks, was developed to facilitate
best practice in addressing Māori ethical concerns by guiding culturally informed policy and …

Purpose: Comprehensive genomic analysis including exome and genome sequencing is
increasingly being utilized in research studies, leading to the generation of incidental …

The past 15 years has seen considerable changes in the research environment. These
changes include the development of new sophisticated genetic and genomic technologies …

We provide a mini‐review of how biobanks can support clinical genetics in the era of
personalized medicine. We discuss types of biobanks, including disease specific and …

Published guidelines suggest that research results and incidental findings should be offered
to study participants under some circumstances. Although some have argued against the …

Purpose: We describe parental attitudes toward the return of targeted and incidental
genomic research results in the setting of high-risk pediatric cancer and inherited childhood …

Biobanks have been heralded as essential tools for translating biomedical research into
practice, driving precision medicine to improve pathways for global healthcare treatment and …

Genomic research—including whole genome sequencing and whole exome sequencing—
has a growing presence in contemporary biomedical investigation. The capacity of …

Introduction Next-generation sequencing (NGS) is transforming the conduct of genetic
research and diagnostic investigation. This creates new challenges as it generates …

Background. Inherited BRCA gene mutations convey a high risk for breast and ovarian
cancer, but current guidelines limit BRCA mutation testing to women with early-onset cancer …