A genetic basis of congenital isolated hypogonadotropic hypogonadism (CHH) can be
defined in almost 50% of cases, albeit not necessarily the complete genetic basis. Next …

The hypothalamus‐pituitary‐thyroid (HPT) axis determines the set point of thyroid hormone
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …

Cranial placodes are specialized regions of the ectoderm, which give rise to various sensory
ganglia and contribute to the pituitary gland and sensory organs of the vertebrate head …

The pituitary gland is a central endocrine organ regulating basic physiological functions,
including growth, the stress response, reproduction, metabolic homeostasis, and lactation …

During mammalian pituitary gland development, distinct cell types emerge from a common
primordium. Appearance of specific cell types occurs in response to opposing signaling …

Organ formation during embryogenesis is a complex process that involves various local cell-
cell interactions at the molecular and mechanical levels. Despite this complexity …

Emergence of distinct cell types from a common primordium during pituitary development
occurs in response to opposing signaling gradients that induce an overlapping temporal and …

Neuroendocrine control mechanisms are observed in all animals that possess a nervous
system. Recent analyses of neuroendocrine functions in invertebrate model systems reveal …

The pituitary develops from the interaction of the infundibulum, a region of the ventral
diencephalon, and Rathke's pouch, a derivative of oral ectoderm. Postnatally, its secretory …

Living organisms represent, in essence, dynamic interactions of high complexity between
membrane‐separated compartments that cannot exist on their own, but reach behaviour in …