The pulmonary route is an interesting route for drug administration, both for effective local
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …

The pharmacokinetic and pharmacodynamic effects of inhaled corticosteroids (ICS) have
shaped the efficacy and safety of these agents in the treatment of asthma. Important …

Asthma is a serious health problem throughout the world. During the past two decades,
many scientific advances have improved our understanding of asthma and ability to manage …

Summary Background The Single combination budesonide–formoterol inhaler Maintenance
And Reliever Therapy (SMART) regimen reduces severe asthma exacerbations in patients …

Objectives: To provide physicians with current guidelines for the diagnosis and optimal
management of asthma in children and adults, including pregnant women and the elderly, in …

Background: Until recently, only two cases of acute adrenal crisis associated with inhaled
corticosteroids (ICS) had been reported worldwide. We identified four additional cases and …

This thoroughly revised and expanded reference provides authoritative discussions on the
physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors …

Eastell R, Reid DM, Compston J, Cooper C, Fogelman I, Francis RM, Hosking DJ, Purdie
DW, Ralston SH, Reeve J, Russell RGG, Stevenson JC, Torgerson DJ (University of …

Asthma is a common chronic inflammatory disorder of the lower respiratory airways in
childhood. The management of asthma exacerbations and the disease control are major …

Abstract Treatment with systemic corticosteroids is known to increase the risk of fractures but
little is known of the fracture risks associated with inhaled corticosteroids. A retrospective …