Triple-negative breast cancer (TNBC) accounts for about 10-20% of all breast cancer cases
and is associated with an unfavorable prognosis. Until recently, treatment options for TNBC …

Introduction Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and
neurodegenerative condition affecting the central nervous system (CNS). Although …

The discovery of selective agonists of cannabinoid receptor 2 (CB 2) is strongly pursued to
successfully tuning endocannabinoid signaling for therapeutic purposes. However, the …

The cannabinoid CB2 receptor was cloned from the promyeloid cell line HL-60 and is
notably expressed in most, if not all leukocyte types. This relatively restricted localization …

Background Neuroinflammation following spinal cord injury (SCI) results in prolonged
neurological damage and locomotor dysfunction. Polarization of microglia is vital to …

Mitochondria are central in the pathogenesis of Parkinson's disease (PD), as they are
involved in oxidative stress, synaptopathy, and other immunometabolic pathways …

Cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2) are components in the
endocannabinoid system that play significant roles in regulating immune responses. There …

Multiple sclerosis (MS) is one of the most common inflammatory neurodegenerative
diseases in young adults and causes neurological abnormalities and disability. We studied …

Acute lymphoblastic leukemia type B (B-ALL) is the most common kind of pediatric leukemia,
characterized by the clonal proliferation of type B lymphoid stem cells. Important progress in …

Cannabinoids (the endocannabinoids, the synthetic cannabinoids, and the
phytocannabinoids) are well known for their various pharmacological properties, including …