Chronic wounds are a common complication in patients with diabetes that often lead to
amputation. These non-healing wounds are described as being stuck in a persistent …

A growing body of evidence suggests that the interaction between immune and metabolic
responses is essential for maintaining tissue and organ homeostasis. These interacting …

The healing of diabetic foot ulcers (DFUs) is a major challenge for clinical treatment because
of the hyperglycemic and acidic microenvironment in the wound area. In this study, a self …

There are a wide variety of dressing techniques and materials available for management of
both acute wounds and chronic non-healing wounds. The primary objective in both the …

Background Wound healing is a complex and dynamic process and a thorough knowledge
of the basics of physiology of wound healing is a must to implement principles of chronic …

The mechanism by which trauma initiates healing remains unclear. Precise understanding
of these events may define interventions for accelerating healing that could be translated to …

Wound healing is a complex biological process that repairs damaged tissues and restores
skin integrity. Insulin, a potent factor of wound healing, has been reported for nearly a …

The healing of chronic wounds remains a key challenge in regenerative medicine. To
promote wound healing, a bioactive wound dressing is required. In this study, a …

The aim of this work was to prepare chitosan nanoparticles containing insulin and to
evaluate its therapeutic activity during wound healing in diabetic rats. The hypothesis that …

Multiple lines of evidence have increasingly suggested a pathogenic connection between
rheumatoid arthritis (RA) and the mechanisms of type 2 diabetes (T2D) in a vicious circle …