Long non-coding RNAs (lncRNAs) play important roles in cancer. They are involved in
chromatin remodeling, as well as transcriptional and post-transcriptional regulation, through …

Diverse classes of RNA, ranging from small to long non-coding RNAs, have emerged as key
regulators of gene expression, genome stability and defence against foreign genetic …

The discovery of long non-coding RNA (lncRNA) has dramatically altered our understanding
of cancer. Here, we describe a comprehensive analysis of lncRNA alterations at …

The onset of heart failure is typically preceded by cardiac hypertrophy, a response of the
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …

Recent advances in RNA-sequencing technologies have led to the discovery of thousands
of previously unannotated noncoding transcripts, including many long noncoding RNAs …

Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and
monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify …

The human 8q24 gene desert contains multiple enhancers that form tissue-specific long-
range chromatin loops with the MYC oncogene, but how chromatin looping at the MYC locus …

To date, there is rapidly increasing evidence for host–microbe interaction at virtually all
levels of complexity, ranging from direct cell‐to‐cell communication to extensive systemic …

Much of the mammalian genome is transcribed, generating long non-coding RNAs
(lncRNAs) that can undergo post-transcriptional surveillance whereby only a subset of the …

Thousands of genes have been well demonstrated to play important roles in cancer
progression. As genes do not function in isolation, they can be grouped into “networks” …