From stable radicals to thermally robust high-spin diradicals and triradicals

C Shu, Z Yang, A Rajca - Chemical Reviews, 2023 - ACS Publications
Stable radicals and thermally robust high-spin di-and triradicals have emerged as important
organic materials due to their promising applications in diverse fields. New fundamental …

Bottlebrush polymers: From controlled synthesis, self-assembly, properties to applications

Z Li, M Tang, S Liang, M Zhang, GM Biesold… - Progress in Polymer …, 2021 - Elsevier
Bottlebrush polymers (BBPs) have emerged as intriguing class of materials for an array of
applications, including supersoft elastomers, organic optoelectronics, templates for crafting …

Molecular bottlebrush prodrugs as mono-and triplex combination therapies for multiple myeloma

A Detappe, HVT Nguyen, Y Jiang, MP Agius… - Nature …, 2023 - nature.com
Cancer therapies often have narrow therapeutic indexes and involve potentially suboptimal
combinations due to the dissimilar physical properties of drug molecules. Nanomedicine …

Activatable multimodal probes for in vivo imaging and theranostics

Y Wang, Y Hu, D Ye - Angewandte Chemie, 2022 - Wiley Online Library
Multimodal imaging, which harnesses two or more imaging modalities to produce
complementary anatomical and molecular information of a living subject, has become as a …

Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia

J Liu, W Bu, J Shi - Chemical reviews, 2017 - ACS Publications
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

[HTML][HTML] Dual key co-activated nanoplatform for switchable MRI monitoring accurate ferroptosis-based synergistic therapy

R Yue, C Zhang, L Xu, Y Wang, G Guan, L Lei, X Zhang… - Chem, 2022 - cell.com
Ferroptosis is of great significance for disease treatment and drug design because of its
effective damage to drug-resistant cells. However, ferroptosis-based therapy presents …

Nanocrystals for Deep-Tissue In Vivo Luminescence Imaging in the Near-Infrared Region

Y Yang, Q Jiang, F Zhang - Chemical Reviews, 2023 - ACS Publications
In vivo imaging technologies have emerged as a powerful tool for both fundamental
research and clinical practice. In particular, luminescence imaging in the tissue-transparent …

Activatable NIR fluorescence/MRI bimodal probes for in vivo imaging by enzyme-mediated fluorogenic reaction and self-assembly

R Yan, Y Hu, F Liu, S Wei, D Fang… - Journal of the …, 2019 - ACS Publications
Stimuli-responsive in situ self-assembly of small molecules to form nanostructures in living
subjects has produced promising tools for molecular imaging and tissue engineering …

A nanostrategy for efficient imaging‐guided antitumor therapy through a stimuli‐responsive branched polymeric prodrug

H Cai, X Dai, X Wang, P Tan, L Gu, Q Luo… - Advanced …, 2020 - Wiley Online Library
A stimuli‐responsive polymeric prodrug‐based nanotheranostic system with imaging agents
(cyanine5. 5 and gadolinium‐chelates) and a therapeutic agent paclitaxel (PTX) is prepared …

Polymeric nanostructures for imaging and therapy

M Elsabahy, GS Heo, SM Lim, G Sun… - Chemical …, 2015 - ACS Publications
Medical diagnosis and therapy are essential for providing patients with proper care,
although inefficient diagnosis and therapy are usually associated with either improper …