Background The promises of improved health care and health research through data-
intensive applications rely on a growing amount of health data. At the core of large-scale …

The collection and use of biological samples and data for genetic research, or for storage in
a biobank or databank for future research, impacts upon many fundamental rights, including …

Important advances in genetics research have been made in recent years. Such advances
have facilitated the availability of huge amounts of genetic information that could potentially …

A biobank is an organized collection of biological human material and its associated
information stored for research according to regulations under institutional responsibility …

Objectives Real-world data (RWD) and real-world evidence (RWE) can provide extensive
information on healthcare for use in health technology assessment and decision making …

Irreproducibility of research results is one of the major contributing factors to the failure of
translating basic research results into tangible bedside progress. To address this, the …

The rise of precision medicine has led to an unprecedented focus on human biological
material in biomedical research. In addition, rapid advances in stem cell technology …

Background Multigene panel testing by next-generation sequencing (MGP-NGS) enables
the detection of germline pathogenic or likely pathogenic variants (PVs/LPVs) in genes …

Background Empirical research can become relevant for bioethics in at least two ways. First,
by informing the development or refinement of ethical recommendations. Second, by …

Biobanking efforts, to establish and grow the pool of available tissue from which evidence on
aetiology, therapeutic susceptibility and prognosis of various diseases, have been underway …