Ketamine in bipolar disorder: a review
A Wilkowska, Ł Szałach, WJ Cubała - … disease and treatment, 2020 - Taylor & Francis
Bipolar disorder (BD) is a psychiatric illness associated with high morbidity, mortality and
suicide rate. It has neuroprogressive course and a high rate of treatment resistance. Hence …
suicide rate. It has neuroprogressive course and a high rate of treatment resistance. Hence …
Strategies for treatment-resistant depression: lessons learned from animal models
GZ Réus, AB de Moura, LA Borba… - Molecular …, 2019 - karger.com
Around 300 million individuals are affected by major depressive disorder (MDD) in the
world. Despite this high number of affected individuals, more than 50% of patients do not …
world. Despite this high number of affected individuals, more than 50% of patients do not …
Vesicular glutamate transporter 1 (VGLUT1)-mediated glutamate release and membrane GluA1 activation is involved in the rapid antidepressant-like effects of …
H Yu, M Li, D Zhou, D Lv, Q Liao, Z Lou, M Shen… - …, 2018 - Elsevier
Emerging data have identified certain drugs such as scopolamine as rapidly acting
antidepressants for major depressive disorder (MDD) that increase glutamate release and …
antidepressants for major depressive disorder (MDD) that increase glutamate release and …
Plasma indoleamine-2, 3-dioxygenase (IDO) is increased in drug-naï ve major depressed patients and treatment with sertraline and ketoprofen normalizes IDO in …
HK Al-Hakeim, AJ Twayej… - CNS & Neurological …, 2020 - ingentaconnect.com
Background: Major Depression Disorder (MDD) is accompanied by an immune response
characterized by increased levels of inflammatory and immune-regulatory cytokines and …
characterized by increased levels of inflammatory and immune-regulatory cytokines and …
The expression of agmatinase manipulates the affective state of rats subjected to chronic restraint stress
S Yan, C Xu, M Yang, H Zhang, Y Cheng, Z Xue… - …, 2023 - Elsevier
Agmatine is an endogenous polyamine produced from l-arginine and degraded by
agmatinase (AGMAT). Studies in humans and animals have shown that agmatine has …
agmatinase (AGMAT). Studies in humans and animals have shown that agmatine has …
Rapid antidepressant actions of imipramine potentiated by zinc through PKA-dependented regulation of mTOR and CREB signaling
Y Huang, D Xu, H Xiang, S Yan, F Sun, Z Wei - … and biophysical research …, 2019 - Elsevier
The slow onset of traditional antidepressants has become an urgent clinical issue,
researchers are constantly exploring new antidepressants with prompt action. Previous …
researchers are constantly exploring new antidepressants with prompt action. Previous …
The associations between central nervous system diseases and haemostatic disorders
M Podsiedlik, M Markowicz-Piasecka… - CNS & Neurological …, 2019 - ingentaconnect.com
The aim of this review was to examine the relationship between the occurrence of central
nervous system (CNS) diseases, the medicines used in their treatment and the blood …
nervous system (CNS) diseases, the medicines used in their treatment and the blood …