Small RNAs (sRNAs), particularly those that act by limited base pairing with mRNAs, are part
of most regulatory networks in bacteria. In many cases, the base‐pairing interaction is …

Bacterial transformation is a programmed process resulting in genetic transfer and diversity.
It relies on the development of competence via regulatory circuits which are diverse and …

All streptococcal genomes encode the alternative sigma factor SigX and 21 SigX‐dependent
proteins required for genetic transformation, yet no pyogenic streptococci are known to …

Research into post‐transcriptional control of mRNAs by small noncoding RNAs (sRNAs) in
the model bacteria Escherichia coli and Salmonella enterica has mainly focused on sRNAs …

The bacterial pathogen Legionella pneumophila exploits host cell vesicle transport by
transiently manipulating the activity of the small guanosine triphosphatase (GTPase) Rab1 …

Intracellular pathogens exploit host cell functions to create a replication niche inside
eukaryotic cells. The causative agent of Legionnaires' disease, the γ-proteobacterium …

Legionella pneumophila requires the Dot/Icm protein translocation system to replicate within
host cells as a critical component of Legionnaire's pneumonia. None of the known individual …

Background Legionella pneumophila is an intracellular pathogen of environmental
protozoa. When humans inhale contaminated aerosols this bacterium may cause a severe …

Natural transformation by competence is a major mechanism of horizontal gene transfer in
bacteria. Competence is defined as the genetically programmed physiological state that …

A highly conserved DNA uptake system allows many bacteria to actively import and
integrate exogenous DNA. This process, called natural transformation, represents a major …