Treatment emergent Dolutegravir resistance mutations in individuals naïve to HIV-1 integrase inhibitors: A rapid scoping review
K Tao, SY Rhee, C Chu, A Avalos, AK Ahluwalia… - Viruses, 2023 - mdpi.com
Background: Dolutegravir (DTG)-based antiretroviral therapy (ART) rarely leads to
virological failure (VF) and drug resistance in integrase strand transfer inhibitor (INSTI)-naïve …
virological failure (VF) and drug resistance in integrase strand transfer inhibitor (INSTI)-naïve …
Dolutegravir resistance in sub-Saharan Africa: should resource-limited settings be concerned for future treatment?
D Kamori, G Barabona - Frontiers in Virology, 2023 - frontiersin.org
In sub-Saharan Africa (SSA) the burden of non-nucleoside reverse transcriptase inhibitor
(NNRTI) HIV drug resistance (HIVDR) has been high over the years. Therefore, in 2018 the …
(NNRTI) HIV drug resistance (HIVDR) has been high over the years. Therefore, in 2018 the …
High viral suppression and detection of dolutegravir-resistance associated mutations in treatment-experienced Tanzanian adults living with HIV-1 in Dar es Salaam
To curb HIV infection rate in Tanzania, antiretroviral therapy (ART) has been scaled up since
2006, and in 2019, the country shifted to regimen including dolutegravir as a default first line …
2006, and in 2019, the country shifted to regimen including dolutegravir as a default first line …
Prevalence of Emergent Dolutegravir Resistance Mutations in People Living with HIV: A Rapid Scoping Review
C Chu, K Tao, V Kouamou, A Avalos, J Scott, PM Grant… - Viruses, 2024 - mdpi.com
Background: Dolutegravir (DTG) is a cornerstone of global antiretroviral (ARV) therapy
(ART) due to its high efficacy and favorable tolerability. However, limited data exist regarding …
(ART) due to its high efficacy and favorable tolerability. However, limited data exist regarding …
[HTML][HTML] Real-world prevalence of integrase inhibitor resistance and virological failure since adoption as guideline-preferred therapy
J Januszka, E Drwiega, R Burgos, R Smith… - Drugs in …, 2024 - ncbi.nlm.nih.gov
Background Limited data reporting real-world prevalence of integrase strand transfer
inhibitor resistance (INSTI-R) in the USA are available because their recommendation as …
inhibitor resistance (INSTI-R) in the USA are available because their recommendation as …
Emergence of acquired dolutegravir resistance in treatment-experienced people with HIV in Lesotho
N Tschumi, B Lukau, K Tlali, L Motaboli… - Clinical Infectious …, 2024 - academic.oup.com
Abstract Background Since 2019, the World Health Organization has recommended
dolutegravir-based antiretroviral therapy (ART) as the preferred regimen for HIV …
dolutegravir-based antiretroviral therapy (ART) as the preferred regimen for HIV …
Population Effectiveness of Dolutegravir Implementation in Uganda-A Prospective Observational Cohort Study (DISCO): 48-week Results
SM McCluskey, WR Muyindike… - The Journal of …, 2024 - academic.oup.com
Background Tenofovir/lamivudine/dolutegravir (TLD) is the preferred first-line antiretroviral
therapy (ART) regimen for people with HIV (PWH), including those who were previously …
therapy (ART) regimen for people with HIV (PWH), including those who were previously …
A Comprehensive Literature Review of Treatment-Emergent Integrase Resistance with Dolutegravir-Based Regimens in Real-World Settings
C Henegar, E Letang, R Wang, C Hicks, D Fox… - Viruses, 2023 - mdpi.com
After a decade of dolutegravir (DTG) use in various antiretroviral therapy combinations and
in diverse populations globally, it is critical to identify HIV strains with reduced drug …
in diverse populations globally, it is critical to identify HIV strains with reduced drug …
Virological Findings and Treatment Outcomes of Cases That Developed Dolutegravir Resistance in Malawi's National HIV Treatment Program
H Kanise, JJ van Oosterhout, P Bisani, J Songo… - Viruses, 2023 - mdpi.com
Millions of Africans are on dolutegravir-based antiretroviral therapy (ART), but few detailed
descriptions of dolutegravir resistance and its clinical management exist. We reviewed HIV …
descriptions of dolutegravir resistance and its clinical management exist. We reviewed HIV …
Risk of Emergent Dolutegravir Resistance Mutations In People Living With HIV: A Rapid Scoping Review
C Chu, K Tao, V Kouamou, A Avalos, J Scott, PM Grant… - medRxiv, 2024 - medrxiv.org
Background: Dolutegravir (DTG) is a cornerstone of global antiretroviral (ARV) therapy
(ART) due to its high efficacy and favorable tolerability. However, limited data exist regarding …
(ART) due to its high efficacy and favorable tolerability. However, limited data exist regarding …