Activated microglial cells play an important role in immune and inflammatory responses in
central nervous system and neurodegenerative diseases. Many pro-apoptotic pathways are …

The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1, HO-2),
catalyze the rate-limiting step in the metabolic conversion of heme to the bile pigments (ie …

Insects possess an immune system that protects them from attacks by various pathogenic
microorganisms that would otherwise threaten their survival. Immune mechanisms may deal …

Background, aim, and scope The use of fish embryos is not regulated by current legislations
on animal welfare and is therefore considered as a refinement, if not replacement of animal …

Fucoxanthin is a marine carotenoid exhibiting several health benefits. The anti-cancer effect
of fucoxanthin and its deacetylated metabolite, fucoxanthinol, is well documented. In view of …

The aim of this study was to explore the intracellular mechanisms underlying the
cardiovascular toxicity of air particulate matter (PM) with an aerodynamic diameter of less …

One of the hallmark features in the neurodegenerative disorders (NDDs) is the accumulation
of aggregated and/or non-functional protein in the cellular milieu. Post-translational …

Hepatocellular carcinoma (HCC) is a fatal disease with limited therapeutic choices. The
stroma-rich tumor microenvironment hinders the in vivo delivery of most nanomedicines …

SUMMARY The Mediterranean blue mussel, Mytilus galloprovincialis, an invasive species in
California, has displaced the more heat-sensitive native congener, Mytilus trossulus, from its …

The recent new developments in technology with culture-independent techniques including
genome sequencing methodologies shed light on the identification of microbiota bacterial …