Homotypic fusion of immature secretory granules during maturation requires syntaxin 6
Homotypic fusion of immature secretory granules (ISGs) gives rise to mature secretory
granules (MSGs), the storage compartment in endocrine and neuroendocrine cells for …
granules (MSGs), the storage compartment in endocrine and neuroendocrine cells for …
[HTML][HTML] Calcium and calmodulin in membrane fusion
RD Burgoyne, MJ Clague - Biochimica et Biophysica Acta (BBA)-Molecular …, 2003 - Elsevier
Regulated exocytosis was the first intracellular membrane fusion step that was suggested to
involve both Ca2+ and calmodulin. In recent years, it has become clear that calmodulin is …
involve both Ca2+ and calmodulin. In recent years, it has become clear that calmodulin is …
Relationships between EEA1 binding partners and their role in endosome fusion
Homotypic fusion between early endosomes requires the phosphatidylinositol 3-phosphate
(PI3P)-binding protein, Early Endosomal Autoantigen 1 (EEA1). We have investigated the …
(PI3P)-binding protein, Early Endosomal Autoantigen 1 (EEA1). We have investigated the …
Structural basis for endosomal targeting by FYVE domains
A Hayakawa, SJ Hayes, DC Lawe… - Journal of Biological …, 2004 - ASBMB
The FYVE domain is a conserved protein motif characterized by its ability to bind with high
affinity and specificity to phosphatidylinositol 3-phosphate (PI (3) P), a phosphoinositide …
affinity and specificity to phosphatidylinositol 3-phosphate (PI (3) P), a phosphoinositide …
Arf6-independent GPI-anchored protein-enriched early endosomal compartments fuse with sorting endosomes via a Rab5/phosphatidylinositol-3′-kinase …
In the process of internalization of molecules from the extracellular milieu, a cell uses
multiple endocytic pathways, consequently generating different endocytic vesicles. These …
multiple endocytic pathways, consequently generating different endocytic vesicles. These …
New insights into membrane trafficking and protein sorting
MC Derby, PA Gleeson - International review of cytology, 2007 - Elsevier
Protein transport in the secretory and endocytic pathways is a multistep process involving
the generation of transport carriers loaded with defined sets of cargo, the shipment of the …
the generation of transport carriers loaded with defined sets of cargo, the shipment of the …
Syntaxin 6: the promiscuous behaviour of a SNARE protein
Vesicle flow within the cell is responsible for the dynamic maintenance of and
communication between intracellular compartments. In addition, vesicular transport is crucial …
communication between intracellular compartments. In addition, vesicular transport is crucial …
Confocal imaging and tracking of the exocytotic routes for D‐serine‐mediated gliotransmission
Abstract d‐Serine is an astrocyte‐derived regulator for N‐methyl‐d‐aspartate receptors, but
the intracellular routes of its trafficking are still largely unknown. Here, we combined confocal …
the intracellular routes of its trafficking are still largely unknown. Here, we combined confocal …
[HTML][HTML] Endocytosis and signaling cascades: a close encounter
V Cavalli, M Corti, J Gruenberg - FEBS letters, 2001 - Elsevier
Internalization of receptors and other cell surface components is well known to occur via
clathrin-mediated endocytosis, although other less well characterized pathways are also …
clathrin-mediated endocytosis, although other less well characterized pathways are also …
[HTML][HTML] Mitotic partitioning of endosomes and lysosomes
T Bergeland, J Widerberg, O Bakke, TW Nordeng - Current Biology, 2001 - cell.com
Background: Some of the mechanisms underlying cell division and partitioning of the
cellular components into the daughter cells are well known. Within the endomembrane …
cellular components into the daughter cells are well known. Within the endomembrane …