Selenium: an antioxidant with a critical role in anti-aging

G Bjørklund, M Shanaida, R Lysiuk, H Antonyak… - Molecules, 2022 - mdpi.com
Aging is characterized by an imbalance between damage inflicted by reactive oxygen
species (ROS) and the antioxidative defenses of the organism. As a significant nutritional …

The role of minerals in the optimal functioning of the immune system

C Weyh, K Krüger, P Peeling, L Castell - Nutrients, 2022 - mdpi.com
Minerals fulfil a wide variety of functions in the optimal functioning of the immune system.
This review reports on the minerals that are essential for the immune system's function and …

[HTML][HTML] Nutrition, immunity and COVID-19

PC Calder - BMJ nutrition, prevention & health, 2020 - ncbi.nlm.nih.gov
The immune system protects the host from pathogenic organisms (bacteria, viruses, fungi,
parasites). To deal with this array of threats, the immune system has evolved to include a …

Selenium, selenoproteins, and immunity

JC Avery, PR Hoffmann - Nutrients, 2018 - mdpi.com
Selenium is an essential micronutrient that plays a crucial role in development and a wide
variety of physiological processes including effect immune responses. The immune system …

Oral hydrogel microbeads-mediated in situ synthesis of selenoproteins for regulating intestinal immunity and microbiota

J Ouyang, B Deng, B Zou, Y Li, Q Bu… - Journal of the …, 2023 - ACS Publications
Selenoprotein plays a crucial role in immune cells and inflammatory regulation. However, as
a protein drug that is easily denatured or degraded in the acidic environment of the stomach …

Selenium, selenoproteins and viral infection

OM Guillin, C Vindry, T Ohlmann, L Chavatte - Nutrients, 2019 - mdpi.com
Reactive oxygen species (ROS) are frequently produced during viral infections. Generation
of these ROS can be both beneficial and detrimental for many cellular functions. When …

Toxicology and pharmacology of synthetic organoselenium compounds: An update

CW Nogueira, NV Barbosa, JBT Rocha - Archives of Toxicology, 2021 - Springer
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

[HTML][HTML] Selenium stimulates the antitumour immunity: Insights to future research

A Razaghi, M Poorebrahim, D Sarhan… - European Journal of …, 2021 - Elsevier
Selenium is an essential trace element for regulating immune functions through redox-
regulating activity of selenoproteins (eg glutathione peroxidase), protecting immune cells …

Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections

H Sies, MJ Parnham - Free Radical Biology and Medicine, 2020 - Elsevier
Ebselen is an organoselenium compound exhibiting hydroperoxide-and peroxynitrite-
reducing activity, acting as a glutathione peroxidase and peroxiredoxin enzyme mimetic …

Molecular mechanisms in autoimmune thyroid disease

H Vargas-Uricoechea - Cells, 2023 - mdpi.com
The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …