[HTML][HTML] Inhibiting mir-34a-5p regulates doxorubicin-induced autophagy disorder and alleviates myocardial pyroptosis by targeting Sirt3-AMPK pathway

Z Zhong, Y Gao, J Zhou, F Wang, P Zhang, S Hu… - Biomedicine & …, 2023 - Elsevier
Doxorubicin (DOX) is a commonly used chemotherapy drug widely applied in various
cancers such as breast cancer, leukemia, and sarcomas. However, its usage is limited by …

Research progress on the role and mechanism of Sirtuin family in doxorubicin cardiotoxicity

X Zhang, C Huang, Y Hou, S Jiang, Y Zhang, S Wang… - Phytomedicine, 2024 - Elsevier
Background Doxorubicin (DOX) is a widely utilized anthracycline chemotherapy drug in
cancer treatment, yet its efficacy is hindered by both short-term and long-term cardiotoxicity …

The role of the ER stress sensor IRE1 in cardiovascular diseases

L Zhou, X Zhu, S Lei, Y Wang, Z Xia - Molecular and Cellular Biochemistry, 2024 - Springer
Despite enormous advances in the treatment of cardiovascular diseases, including I/R injury
and heart failure, heart diseases remain a leading cause of mortality worldwide. Inositol …

[HTML][HTML] Activation of Sirtuin3 by honokiol ameliorates alveolar epithelial cell senescence in experimental silicosis via the cGAS-STING pathway

Q Zhou, G Yi, M Chang, N Li, Y Bai, H Li, S Yao - Redox Biology, 2024 - Elsevier
Background Silicosis, characterized by interstitial lung inflammation and fibrosis, poses a
significant health threat. ATII cells play a crucial role in alveolar epithelial repair and …

Gossypin Regulated Doxorubicin-Induced Oxidative Stress and Inflammation in H9c2 Cardiomyocyte Cells

Y Yazğan, B Yazğan - Medical Records, 2024 - dergipark.org.tr
Aim: Doxorubicin (DOX), an anthracycline, is widely used in chemotherapy due to its
effectiveness in fighting many cancers. Experimental and clinical studies prove that this drug …

[PDF][PDF] Фармопіка пацієнта з гострим інфарктом міокарда та коморбідною патологією

ВО Шевченко, ВС Потаскалова - 2024 - ir.librarynmu.com
Серцево-судинна патологіє посідає провідну роль в смертності та івалідизації людей у
всьому світі. Кількість людей, які мають патологію серцево-судинної системи (ССС) …