Obesity, adipose tissue and vascular dysfunction

M Koenen, MA Hill, P Cohen, JR Sowers - Circulation research, 2021 - Am Heart Assoc
Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity
are strongly associated with comorbidities such as hypertension and insulin resistance …

[PDF][PDF] Oxidative stress and inflammatory markers in prediabetes and diabetes.

K Luc, A Schramm-Luc, TJ Guzik… - Journal of Physiology & …, 2019 - researchgate.net
Prediabetes is a state of elevated plasma glucose in which the threshold for diabetes has
not yet been reached and can predispose to the development of type 2 diabetes and …

Pathophysiology of hypertension: the mosaic theory and beyond

DG Harrison, TM Coffman, CS Wilcox - Circulation research, 2021 - Am Heart Assoc
Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that
hypertension is the result of many factors that interact to raise blood pressure and cause end …

[HTML][HTML] The compelling link between physical activity and the body's defense system

DC Nieman, LM Wentz - Journal of sport and health science, 2019 - Elsevier
This review summarizes research discoveries within 4 areas of exercise immunology that
have received the most attention from investigators:(1) acute and chronic effects of exercise …

Effect of vitamin D3 supplements on development of advanced cancer: a secondary analysis of the VITAL randomized clinical trial

PD Chandler, WY Chen, ON Ajala, A Hazra… - JAMA network …, 2020 - jamanetwork.com
Importance Epidemiologic and trial data suggest that vitamin D supplementation may reduce
metastatic cancer and cancer mortality, reflecting shared biological pathways. Objective To …

[HTML][HTML] The short-chain fatty acid acetate in body weight control and insulin sensitivity

MA González Hernández, EE Canfora, JWE Jocken… - Nutrients, 2019 - mdpi.com
The interplay of gut microbiota, host metabolism, and metabolic health has gained increased
attention. Gut microbiota may play a regulatory role in gastrointestinal health, substrate …

[HTML][HTML] Cardiovascular risk and obesity

C Cercato, FA Fonseca - Diabetology & metabolic syndrome, 2019 - Springer
Background This is an overview of the mechanisms of obesity and its relation to
cardiovascular risks, describing the available treatment options to manage this condition …

[HTML][HTML] Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms

JR Petrie, TJ Guzik, RM Touyz - Canadian Journal of Cardiology, 2018 - Elsevier
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as
frequent in patients with diabetes compared with those who do not have diabetes. Moreover …

Sarcoidosis: Epidemiology and clinical insights

M Rossides, P Darlington, S Kullberg… - Journal of internal …, 2023 - Wiley Online Library
Sarcoidosis is characterized by noncaseating granulomas which form in almost any part of
the body, primarily in the lungs and/or thoracic lymph nodes. Environmental exposures in …

Vascular smooth muscle contraction in hypertension

RM Touyz, R Alves-Lopes, FJ Rios… - Cardiovascular …, 2018 - academic.oup.com
Hypertension is a major risk factor for many common chronic diseases, such as heart failure,
myocardial infarction, stroke, vascular dementia, and chronic kidney disease …