Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation
J Yodoi, T Uchiyama - Immunology today, 1992 - cell.com
HTLV-I, the etiological agent in adult T-cell leukemia, has also been strongly implicated in a
number of non-neoplastic T-cell-associated diseases. Here, Junji Yodoi and Takashi …
number of non-neoplastic T-cell-associated diseases. Here, Junji Yodoi and Takashi …
Identification of a site in glutamate receptor subunits that controls calcium permeability
RI Hume, R Dingledine, SF Heinemann - Science, 1991 - science.org
The neurotransmitter glutamate mediates excitatory synaptic transmission throughout the
brain. A family of genes encoding subunits of the non-N-methyl-D-aspartate (non-NMDA) …
brain. A family of genes encoding subunits of the non-N-methyl-D-aspartate (non-NMDA) …
ATL‐derived factor (ADF), an IL‐2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol‐reduction in the IL‐2 receptor induction.
Y Tagaya, Y Maeda, A Mitsui, N Kondo, H Matsui… - The EMBO …, 1989 - embopress.org
HTLV‐I transformed T cells not only express a large number of interleukin‐2 receptors [IL‐
2R/p55 (Tac)], but also produce a factor named ATL‐derived factor (ADF) that augments the …
2R/p55 (Tac)], but also produce a factor named ATL‐derived factor (ADF) that augments the …
Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro.
A Tanaka, C Takahashi, S Yamaoka… - Proceedings of the …, 1990 - National Acad Sciences
Human T-cell leukemia virus type I (HTLV-I) is a causative agent of adult T-cell leukemia
(ATL). To elucidate the role of HTLV-I in leukemogenesis, we examined the biological …
(ATL). To elucidate the role of HTLV-I in leukemogenesis, we examined the biological …
Induction of inflammatory arthropathy resembling rheumatoid arthritis in mice transgenic for HTLV-I
Y Iwakura, M Tosu, E Yoshida, M Takiguchi, K Sato… - Science, 1991 - science.org
Human T cell leukemia virus type-I (HTLV-I) is the etiologic agent of adult T cell leukemia
and has also been suggested to be involved in other diseases such as chronic arthritis or …
and has also been suggested to be involved in other diseases such as chronic arthritis or …
ADF, a growth-promoting factor derived from adult T cell leukemia and homologous to thioredoxin: involvement in lymphocyte immortalization by HTLV-I and EBV
J Yodoi, T Tursz - Advances in cancer research, 1991 - Elsevier
Publisher Summary Adult T-cell leukemia-derived factor (ADF) plays an important role in the
transforming properties of HTLV-I by interfering with the expression of the interleukin-2 …
transforming properties of HTLV-I by interfering with the expression of the interleukin-2 …
Sequence requirements for nucleolar localization of human T cell leukemia virus type I pX protein, which regulates viral RNA processing
Summary The posttranscriptional regulator (~ 27~-“') of human T cell leukemia virus type I
(HTLV-I) is located predominantly in the cell nucleolus. A highly basic aminoterminal …
(HTLV-I) is located predominantly in the cell nucleolus. A highly basic aminoterminal …
Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat
K Nagata, K Ohtani, M Nakamura… - Journal of virology, 1989 - Am Soc Microbiol
We examined the ability of the trans-acting factor p40tax of human T-cell leukemia virus type
I (HTLV-I), which is thought to be a crucial molecule in T-cell transformation by HTLV-I, to …
I (HTLV-I), which is thought to be a crucial molecule in T-cell transformation by HTLV-I, to …
Characterization of high-affinity receptors for interleukin 5 on interleukin 5-dependent cell lines.
S Mita, A Tominaga, Y Hitoshi… - Proceedings of the …, 1989 - National Acad Sciences
Interleukin 5 (IL-5) is a glycosylated polypeptide that acts as a key factor for B-cell growth
and differentiation. We demonstrated previously that there are two classes (high and low …
and differentiation. We demonstrated previously that there are two classes (high and low …
Nucleolar targeting signal of human T-cell leukemia virus type I rex-encoded protein is essential for cytoplasmic accumulation of unspliced viral mRNA.
The posttranscriptional regulator (rex) of human T-cell leukemia virus type I is known to be
located predominantly in the cell nucleolus and to induce the accumulation of gag and env …
located predominantly in the cell nucleolus and to induce the accumulation of gag and env …