TIGIT and PD-1 may serve as potential prognostic biomarkers for gastric cancer
D Xu, E Zhao, C Zhu, W Zhao, C Wang, Z Zhang… - Immunobiology, 2020 - Elsevier
Gastric Cancer (GC) is the fifth leading cause of cancer-related death in the world, and in
urgent need of specific therapeutic targets to acquire prominent effectiveness. T-cell …
urgent need of specific therapeutic targets to acquire prominent effectiveness. T-cell …
Screening of key genes of sepsis and septic shock using bioinformatics analysis
X Zeng, J Feng, Y Yang, R Zhao, Q Yu… - Journal of …, 2021 - Taylor & Francis
Objective: Sepsis is a disease associated with high mortality. We performed bioinformatic
analysis to identify key biomarkers associated with sepsis and septic shock. Methods: The …
analysis to identify key biomarkers associated with sepsis and septic shock. Methods: The …
[HTML][HTML] Two gene set variation indexes as potential diagnostic tool for sepsis
J Lu, Q Li, Z Wu, Z Zhong, P Ji, H Li, C He… - American journal of …, 2020 - ncbi.nlm.nih.gov
Accurate diagnosis of sepsis remains challenging, new markers or combinations of markers
are urgently needed. In the present study, we screened differentially expressed genes …
are urgently needed. In the present study, we screened differentially expressed genes …
[HTML][HTML] Diagnostic and predictive values of pyroptosis-related genes in sepsis
X Wang, Z Guo, Z Wang, H Liao, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Background Sepsis is an organ dysfunction syndrome caused by the body's dysregulated
response to infection. Yet, due to the heterogeneity of this disease process, the diagnosis …
response to infection. Yet, due to the heterogeneity of this disease process, the diagnosis …
[HTML][HTML] miR‑23a downregulation modulates the inflammatory response by targeting ATG12‑mediated autophagy
X Si, D Cao, J Chen, Y Nie, Z Jiang… - Molecular …, 2018 - spandidos-publications.com
Autophagy, part of the innate immune defense mechanisms, is activated during the initial
phase of septic insult. Previous studies indicated that micro (mi) RNAs are additionally …
phase of septic insult. Previous studies indicated that micro (mi) RNAs are additionally …
[HTML][HTML] Estimates of gene ensemble noise highlight critical pathways and predict disease severity in H1N1, COVID-19 and mortality in sepsis patients
Finding novel biomarkers for human pathologies and predicting clinical outcomes for
patients is challenging. This stems from the heterogeneous response of individuals to …
patients is challenging. This stems from the heterogeneous response of individuals to …
Targeted LC-MS/MS for the evaluation of proteomics biomarkers in the blood of neonates with necrotizing enterocolitis and late-onset sepsis
Late-onset sepsis (LOS) and necrotizing enterocolitis (NEC) are severe life-threatening
conditions for neonates. Accurate, early diagnosis and timely initiation of treatment are …
conditions for neonates. Accurate, early diagnosis and timely initiation of treatment are …
Time series gene expression profiles analysis identified several potential biomarkers for sepsis
S Zhang, N Li, W Chen, Q Fu, Y Liu - DNA and Cell Biology, 2020 - liebertpub.com
Sepsis is a life-threatening disorder and leads to organ dysfunction and death. Therefore,
searching for more alternative biomarkers is of great significance for sepsis assessment and …
searching for more alternative biomarkers is of great significance for sepsis assessment and …
Identification of novel biomarkers for sepsis diagnosis via serum proteomic analysis using iTRAQ‐2D‐LC‐MS/MS
M Li, R Ren, M Yan, S Chen, C Chen… - Journal of Clinical …, 2022 - Wiley Online Library
Background Sepsis is a common cause of morbidity and mortality in the ICU patients. Early
diagnosis and appropriate patient management is the key to improve the patient survival …
diagnosis and appropriate patient management is the key to improve the patient survival …
[HTML][HTML] B2M is a Biomarker Associated With Immune Infiltration In High Altitude Pulmonary Edema
M Yuan, X Hu, W Xing, X Wu, C Pu, W Guo… - … chemistry & high …, 2023 - ncbi.nlm.nih.gov
Background: High altitude pulmonary edema (HAPE) is a serious mountain sickness with
certain mortality. Its early diagnosis is very important. However, the mechanism of its onset …
certain mortality. Its early diagnosis is very important. However, the mechanism of its onset …