Since immunoglobulin A nephropathy (IgAN) was first described in the seminal papers by
Berger [1, 2], we have learned much descriptively about its epidemiology, associations …

In the era of COVID-19, understanding how our immune system responds to viral infections
is more pertinent than ever. Immunodeficiencies with very low or absent B cells offer a …

It is generally accepted that moderate amounts of exercise improve immune system
functions and hence reduce the risk of infection whereas athletes engaged in regular …

Immunoglobulin A (IgA) is one of the important and most abundant immunoglobulins which
neutralize invading pathogens at mucosal sites. Gut microbial community and their …

IgA nephropathy, the most common primary glomerulonephritis in the world and a frequent
cause of end-stage renal disease, is characterized by typical mesangial deposits of IgA1, as …

Numerous abnormalities of the IgA immune system have been reported in IgAN but the most
consistent finding remains aberrant IgA1 O‐linked glycosylation of the IgA1 hinge region …

Mucosal and parenteral immunizations elicit qualitatively distinct immune responses, and
there is evidence that mucosal immunization can skew the balance of T helper 1 and T …

The oral route of human papillomavirus (HPV) transmission is not fully understood. It has
been suggested that genital infection can act as a reservoir for oral HPV infection. We …

Although more than 20 years have passed since the initial report of IgA nephropathy, the
etiology of this disease is still unclear. Some reports suggest that the tonsil is an important …

Discussion DR. LA VAN Es (Professor of Medicine, Department of Nephrology, Leiden
University Hospital, Leiden, The Netherlands): This patient manifested some unusual …