In recent years, metabolomics, identification and profiling of metabolites, have gained broad
interest compared to other omics technologies and are progressively being utilized for …

Background Innate immunity and metabolites link to the pathogenesis and severity of acute
pancreatitis (AP). However, liver metabolism and its role in immune response and AP …

Acute pancreatitis (AP) is a type of digestive system disease with high mortality. Previous
studies have shown that gut microbiota can participate in developing and treating acute …

To reveal dysregulated metabolism hallmark that was associated with a severe acute
pancreatitis (SAP) phenotype. In this study, LC-MS/MS-based targeted metabolomics was …

Background Cholestatic liver diseases (CLD) comprise a variety of disorders of bile
formation, which causes chronic exposure to bile acid (BA) in the liver generally and results …

Background Pancreatitis is a common exocrine inflammatory disease of the pancreas and
lacks specific medication currently. Rhei Radix et Rhizoma (RR) and its anthraquinone …

Among drug-induced adverse events, pancreatitis is life-threatening and results in
substantial morbidity. A prototype example is the pancreatitis caused by asparaginase, a …

Introduction Infected pancreatic necrosis (IPN) is a major cause of mortality in acute
pancreatitis (AP). Currently, no specific strategies are available to predict the development of …

Background Acute pancreatitis (AP) is an inflammatory disorder of pancreas that lacks
effective specific drugs as well as gold standard laboratory tests for diagnosis and severity …

Untargeted Nuclear Magnetic Resonance (NMR) metabolomics of polar extracts from the
pancreata of a caerulin-induced mouse model of pancreatitis (Pt) and of a transgenic mouse …